Compile Data Set for Download or QSAR
Report error Found 75 Enz. Inhib. hit(s) with all data for entry = 50021995
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50605104(CHEMBL5180980)
Affinity DataKd: <0.100nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646921(CHEMBL5592260)
Affinity DataKd:  2nMAssay Description:Binding affinity to GST-tagged human MDM2 extracted from Escherichia coli BL21 (DE3) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50241617(CHEMBL4068667)
Affinity DataIC50: 3nMAssay Description:Inhibition of MDMX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50241631(CHEMBL4095983)
Affinity DataIC50: 6nMAssay Description:Inhibition of MDMX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50241631(CHEMBL4095983)
Affinity DataIC50: 8nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646930(CHEMBL2313487)
Affinity DataIC50: 10nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646921(CHEMBL5592260)
Affinity DataKd:  10nMAssay Description:Binding affinity to N-terminal human MDMX (22 to 110 residues) extracted from Escherichia coli BL21 (DE3) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50403525(CHEMBL3220312)
Affinity DataIC50: 17nMAssay Description:Inhibition of MDMX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50229787(CHEMBL191334 | 4-((4S,5R)-4,5-bis(4-chlorophenyl)-...)
Affinity DataKd:  20nMAssay Description:Binding affinity to GST-tagged human MDM2 extracted from Escherichia coli BL21 (DE3) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50605104(CHEMBL5180980)
Affinity DataKd:  20nMAssay Description:Binding affinity to MDMX (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646924(CHEMBL5593446)
Affinity DataIC50: 20nMAssay Description:Inhibition of MDMX (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646924(CHEMBL5593446)
Affinity DataIC50: 20nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646930(CHEMBL2313487)
Affinity DataIC50: 20nMAssay Description:Inhibition of MDMX (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50229787(CHEMBL191334 | 4-((4S,5R)-4,5-bis(4-chlorophenyl)-...)
Affinity DataKd:  20nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50014089(CHEMBL1236726)
Affinity DataKd:  20nMAssay Description:Binding affinity to His-tagged MDM2 (1 to 110 residues) (unknown origin) assessed as dissociation constant by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50403525(CHEMBL3220312)
Affinity DataIC50: 20nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646934(CHEMBL5593847)
Affinity DataIC50: 30nMAssay Description:Inhibition of MDMX (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646926(CHEMBL5591432)
Affinity DataIC50: 30nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50403482(CHEMBL5267044)
Affinity DataIC50: 30nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646927(CHEMBL5583623)
Affinity DataIC50: 40nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646929(CHEMBL2313485)
Affinity DataIC50: 40nMAssay Description:Inhibition of MDMX (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50403482(CHEMBL5267044)
Affinity DataIC50: 41nMAssay Description:Inhibition of MDMX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646927(CHEMBL5583623)
Affinity DataIC50: 60nMAssay Description:Inhibition of MDMX (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646935(CHEMBL5591474)
Affinity DataIC50: 70nMAssay Description:Inhibition of MDMX (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646925(CHEMBL5592473)
Affinity DataIC50: 70nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646925(CHEMBL5592473)
Affinity DataIC50: 80nMAssay Description:Inhibition of MDMX (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646929(CHEMBL2313485)
Affinity DataIC50: 90nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50241617(CHEMBL4068667)
Affinity DataIC50: 140nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50499318(CHEMBL3735996)
Affinity DataKd:  200nMAssay Description:Binding affinity to MDMX (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646926(CHEMBL5591432)
Affinity DataIC50: 200nMAssay Description:Inhibition of MDMX (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646918(CHEMBL5592613)
Affinity DataKd:  200nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646919(CHEMBL5595055)
Affinity DataKd:  300nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646928(CHEMBL5596017)
Affinity DataIC50: 300nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646923(CHEMBL5592314)
Affinity DataKd:  600nMAssay Description:Binding affinity to N-terminal human MDMX (22 to 110 residues) extracted from Escherichia coli BL21 (DE3) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646922(CHEMBL5592326)
Affinity DataKd:  600nMAssay Description:Binding affinity to N-terminal human MDMX (22 to 110 residues) extracted from Escherichia coli BL21 (DE3) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646915(CHEMBL5595494)
Affinity DataKd:  900nMAssay Description:Binding affinity to N-terminal MDM2 (24 to 109 residues) (unknown origin) extracted from Escherichia coli BL21-Gold (DE3) assessed as dissociation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646917(CHEMBL5593177)
Affinity DataKd:  1.40E+3nMAssay Description:Binding affinity to N-terminal MDM2 (24 to 109 residues) (unknown origin) extracted from Escherichia coli BL21-Gold (DE3) assessed as dissociation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646933(CHEMBL3774508)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of MDMX (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50499318(CHEMBL3735996)
Affinity DataKd:  1.80E+3nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646918(CHEMBL5592613)
Affinity DataKd:  2.50E+3nMAssay Description:Binding affinity to MDMX (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646908(CHEMBL5593887)
Affinity DataKd:  2.70E+3nMAssay Description:Binding affinity to N-terminal MDM2 (24 to 109 residues) (unknown origin) extracted from Escherichia coli BL21-Gold (DE3) assessed as dissociation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646920(CHEMBL5595519)
Affinity DataKd:  3.50E+3nMAssay Description:Binding affinity to GST-tagged human MDM2 extracted from Escherichia coli BL21 (DE3) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646919(CHEMBL5595055)
Affinity DataKd:  3.50E+3nMAssay Description:Binding affinity to MDMX (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646931(CHEMBL5593501)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of MDMX (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646920(CHEMBL5595519)
Affinity DataKd:  4.10E+3nMAssay Description:Binding affinity to N-terminal human MDMX (22 to 110 residues) extracted from Escherichia coli BL21 (DE3) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50499315(CHEMBL3735566)
Affinity DataKd:  5.00E+3nMAssay Description:Binding affinity to MDMX (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50646932(CHEMBL5594228)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of MDMX (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50229787(CHEMBL191334 | 4-((4S,5R)-4,5-bis(4-chlorophenyl)-...)
Affinity DataKd:  6.50E+3nMAssay Description:Binding affinity to MDMX (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50229787(CHEMBL191334 | 4-((4S,5R)-4,5-bis(4-chlorophenyl)-...)
Affinity DataKd:  6.50E+3nMAssay Description:Binding affinity to N-terminal human MDMX (22 to 110 residues) extracted from Escherichia coli BL21 (DE3) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50499315(CHEMBL3735566)
Affinity DataKd:  6.70E+3nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
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