Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50022096
TargetTargeting protein for Xklp2(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648058(CHEMBL5598235)
Affinity DataKd:  18nMAssay Description:Inhibition of 6-His-tagged human Aurora A (126 to 390 residues) expressed in Escherichia coli BL21 (DE3) cells/N-terminal his-tagged/GB-1 fused human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTargeting protein for Xklp2(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648059(CHEMBL5597404)
Affinity DataKd:  19nMAssay Description:Inhibition of 6-His-tagged human Aurora A (126 to 390 residues) expressed in Escherichia coli BL21 (DE3) cells/N-terminal his-tagged/GB-1 fused human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAurora kinase A(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648055(CHEMBL5596260)
Affinity DataKd:  50nMAssay Description:Binding affinity to 6-His-tagged human Aurora A (126 to 390 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation constan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTargeting protein for Xklp2(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648057(CHEMBL5596916)
Affinity DataKd:  63nMAssay Description:Inhibition of 6-His-tagged human Aurora A (126 to 390 residues) expressed in Escherichia coli BL21 (DE3) cells/N-terminal his-tagged/GB-1 fused human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTargeting protein for Xklp2(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648055(CHEMBL5596260)
Affinity DataKd:  79nMAssay Description:Inhibition of 6-His-tagged human Aurora A (126 to 390 residues) expressed in Escherichia coli BL21 (DE3) cells/N-terminal his-tagged/GB-1 fused human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAurora kinase A(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648056(CHEMBL5598288)
Affinity DataKd:  79nMAssay Description:Binding affinity to 6-His-tagged human Aurora A (126 to 390 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation constan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTargeting protein for Xklp2(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648056(CHEMBL5598288)
Affinity DataKd:  100nMAssay Description:Inhibition of 6-His-tagged human Aurora A (126 to 390 residues) expressed in Escherichia coli BL21 (DE3) cells/N-terminal his-tagged/GB-1 fused human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAurora kinase A(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648057(CHEMBL5596916)
Affinity DataKd:  100nMAssay Description:Binding affinity to 6-His-tagged human Aurora A (126 to 390 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation constan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTargeting protein for Xklp2(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648052(CHEMBL5598166)
Affinity DataKd:  158nMAssay Description:Inhibition of 6-His-tagged human Aurora A (126 to 390 residues) expressed in Escherichia coli BL21 (DE3) cells/N-terminal his-tagged/GB-1 fused human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTargeting protein for Xklp2(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648054(CHEMBL5597168)
Affinity DataKd:  200nMAssay Description:Inhibition of 6-His-tagged human Aurora A (126 to 390 residues) expressed in Escherichia coli BL21 (DE3) cells/N-terminal his-tagged/GB-1 fused human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTargeting protein for Xklp2(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648053(CHEMBL5596300)
Affinity DataKd:  955nMAssay Description:Inhibition of 6-His-tagged human Aurora A (126 to 390 residues) expressed in Escherichia coli BL21 (DE3) cells/N-terminal his-tagged/GB-1 fused human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTargeting protein for Xklp2(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648051(CHEMBL5597558)
Affinity DataKd:  1.26E+3nMAssay Description:Inhibition of 6-His-tagged human Aurora A (126 to 390 residues) expressed in Escherichia coli BL21 (DE3) cells/N-terminal his-tagged/GB-1 fused human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTargeting protein for Xklp2(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648057(CHEMBL5596916)
Affinity DataEC50:  1.30E+3nMAssay Description:Inhibition of Aurora A-TPX2 protein-protein interaction in human HeLa cells assessed as mislocalization of aurora A by measuring displacement from sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTargeting protein for Xklp2(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648056(CHEMBL5598288)
Affinity DataEC50:  2.20E+3nMAssay Description:Inhibition of Aurora A-TPX2 protein-protein interaction in human HeLa cells assessed as mislocalization of aurora A by measuring displacement from sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTargeting protein for Xklp2(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648055(CHEMBL5596260)
Affinity DataEC50:  3.50E+3nMAssay Description:Inhibition of Aurora A-TPX2 protein-protein interaction in human HeLa cells assessed as mislocalization of aurora A by measuring displacement from sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTargeting protein for Xklp2(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648059(CHEMBL5597404)
Affinity DataEC50:  3.90E+3nMAssay Description:Inhibition of Aurora A-TPX2 protein-protein interaction in human HeLa cells assessed as reduction in aurora A phosphorylation at Thr288 residue incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTargeting protein for Xklp2(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648057(CHEMBL5596916)
Affinity DataEC50:  4.50E+3nMAssay Description:Inhibition of Aurora A-TPX2 protein-protein interaction in human HeLa cells assessed as reduction in aurora A phosphorylation at Thr288 residue incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTargeting protein for Xklp2(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648054(CHEMBL5597168)
Affinity DataEC50:  5.50E+3nMAssay Description:Inhibition of Aurora A-TPX2 protein-protein interaction in human HeLa cells assessed as mislocalization of aurora A by measuring displacement from sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTargeting protein for Xklp2(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648055(CHEMBL5596260)
Affinity DataEC50:  5.90E+3nMAssay Description:Inhibition of Aurora A-TPX2 protein-protein interaction in human HeLa cells assessed as reduction in aurora A phosphorylation at Thr288 residue incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTargeting protein for Xklp2(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648059(CHEMBL5597404)
Affinity DataEC50:  6.10E+3nMAssay Description:Inhibition of Aurora A-TPX2 protein-protein interaction in human HeLa cells assessed as mislocalization of aurora A by measuring displacement from sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTargeting protein for Xklp2(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648054(CHEMBL5597168)
Affinity DataEC50:  6.40E+3nMAssay Description:Inhibition of Aurora A-TPX2 protein-protein interaction in human HeLa cells assessed as reduction in aurora A phosphorylation at Thr288 residue incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTargeting protein for Xklp2(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648056(CHEMBL5598288)
Affinity DataEC50:  6.90E+3nMAssay Description:Inhibition of Aurora A-TPX2 protein-protein interaction in human HeLa cells assessed as reduction in aurora A phosphorylation at Thr288 residue incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTargeting protein for Xklp2(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648053(CHEMBL5596300)
Affinity DataEC50:  2.00E+4nMAssay Description:Inhibition of Aurora A-TPX2 protein-protein interaction in human HeLa cells assessed as mislocalization of aurora A by measuring displacement from sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTargeting protein for Xklp2(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648053(CHEMBL5596300)
Affinity DataEC50:  2.18E+4nMAssay Description:Inhibition of Aurora A-TPX2 protein-protein interaction in human HeLa cells assessed as reduction in aurora A phosphorylation at Thr288 residue incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTargeting protein for Xklp2(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648050(CHEMBL5597299)
Affinity DataKd:  6.30E+4nMAssay Description:Inhibition of 6-His-tagged human Aurora A (126 to 390 residues) expressed in Escherichia coli BL21 (DE3) cells/N-terminal his-tagged/GB-1 fused human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAurora kinase A(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50648050(CHEMBL5597299)
Affinity DataKd:  1.45E+5nMAssay Description:Binding affinity to 6-His-tagged human Aurora A (126 to 390 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation constan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTargeting protein for Xklp2(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50336491(CHEMBL65369 | 3-Hydroxybenzoate, II | 3-hydroxyben...)
Affinity DataKd:  1.00E+6nMAssay Description:Inhibition of 6-His-tagged human Aurora A (126 to 390 residues) expressed in Escherichia coli BL21 (DE3) cells/N-terminal his-tagged/GB-1 fused human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed