Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50022002
LigandPNGBDBM662623(US20240109865, Example 46.)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of FGFR3 V555L mutant (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM662623(US20240109865, Example 46.)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of wild-type FGFR3 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM662623(US20240109865, Example 46.)
Affinity DataIC50: 2nMAssay Description:Inhibition of FGFR3 V555M mutant (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM662623(US20240109865, Example 46.)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human FLT4 by KINOMEscan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM662623(US20240109865, Example 46.)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of FGFR3 K650M mutant (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM662623(US20240109865, Example 46.)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of FGFR3 K650E mutant (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM662623(US20240109865, Example 46.)
Affinity DataIC50: 7nMAssay Description:Inhibition of human FGFR2 by KINOMEscan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50189781(CHEMBL3828009)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant TEL/VEGFR2 (unknown origin) transduced in mouse BaF3 cells incubated for 48 hrs by Cell Titer Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM662623(US20240109865, Example 46.)
Affinity DataIC50: 11nMAssay Description:Inhibition of human FGFR4 by KINOMEscan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM662623(US20240109865, Example 46.)
Affinity DataIC50: 21nMAssay Description:Inhibition of wild-type FGFR3 (unknown origin) by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM662623(US20240109865, Example 46.)
Affinity DataIC50: 21nMAssay Description:Inhibition of FGFR3 G380R mutant (unknown origin) by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM662623(US20240109865, Example 46.)
Affinity DataIC50: 36nMAssay Description:Inhibition of human JAK2 by KINOMEscan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM662623(US20240109865, Example 46.)
Affinity DataIC50: 65nMAssay Description:Inhibition of human LTK by KINOMEscan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM662623(US20240109865, Example 46.)
Affinity DataIC50: 73nMAssay Description:Inhibition of FGFR3 N540K mutant (unknown origin) by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM662623(US20240109865, Example 46.)
Affinity DataIC50: 108nMAssay Description:Inhibition of human FGFR1 by KINOMEscan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM662581(US20240109865, Example 4. | [4-[5-[5-[(1R)-1- (3,5...)
Affinity DataIC50: 162nMAssay Description:Inhibition of recombinant TEL/VEGFR2 (unknown origin) transduced in mouse BaF3 cells incubated for 48 hrs by Cell Titer Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM662583(US20240109865, Example 6. | 5-[(1R)-1-(3,5- dichlo...)
Affinity DataIC50: 198nMAssay Description:Inhibition of recombinant TEL/VEGFR2 (unknown origin) transduced in mouse BaF3 cells incubated for 48 hrs by Cell Titer Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM662623(US20240109865, Example 46.)
Affinity DataIC50: 201nMAssay Description:Inhibition of human FLT1 by KINOMEscan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM662623(US20240109865, Example 46.)
Affinity DataIC50: 206nMAssay Description:Inhibition of human JAK3 by KINOMEscan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM662586(US20240109865, Example 9. | 1-[4-[5-[5-[(1R)-1- (3...)
Affinity DataIC50: 314nMAssay Description:Inhibition of recombinant TEL/VEGFR2 (unknown origin) transduced in mouse BaF3 cells incubated for 48 hrs by Cell Titer Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM662582(US20240109865, Example 5. | 4-[5-[5-[(1R)-1-(3,5- ...)
Affinity DataIC50: 323nMAssay Description:Inhibition of recombinant TEL/VEGFR2 (unknown origin) transduced in mouse BaF3 cells incubated for 48 hrs by Cell Titer Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM662623(US20240109865, Example 46.)
Affinity DataIC50: 325nMAssay Description:Inhibition of human VEGFR2 by KINOMEscan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM662599(US20240109865, Example 22.)
Affinity DataIC50: 560nMAssay Description:Inhibition of recombinant TEL/VEGFR2 (unknown origin) transduced in mouse BaF3 cells incubated for 48 hrs by Cell Titer Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM662647(US20240109865, Example 70. | 5-[(1R)-1- (3,5-dichl...)
Affinity DataIC50: 586nMAssay Description:Inhibition of recombinant TEL/VEGFR2 (unknown origin) transduced in mouse BaF3 cells incubated for 48 hrs by Cell Titer Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50525939(Balversa | Erdafitinib | Jnj-42756493)
Affinity DataIC50: 627nMAssay Description:Inhibition of recombinant TEL/VEGFR2 (unknown origin) transduced in mouse BaF3 cells incubated for 48 hrs by Cell Titer Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM662584(US20240109865, Example 7. | Methyl 4-[5-[5- [(1R)-...)
Affinity DataIC50: 637nMAssay Description:Inhibition of recombinant TEL/VEGFR2 (unknown origin) transduced in mouse BaF3 cells incubated for 48 hrs by Cell Titer Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM662616(US20240109865, Example 39. | 1-[5-[5-[(1R)-1-(3,5-...)
Affinity DataIC50: 679nMAssay Description:Inhibition of recombinant TEL/VEGFR2 (unknown origin) transduced in mouse BaF3 cells incubated for 48 hrs by Cell Titer Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM662595(US20240109865, Example 18.)
Affinity DataIC50: 864nMAssay Description:Inhibition of recombinant TEL/VEGFR2 (unknown origin) transduced in mouse BaF3 cells incubated for 48 hrs by Cell Titer Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50647021(CHEMBL5594969)
Affinity DataIC50: 887nMAssay Description:Inhibition of recombinant TEL/VEGFR2 (unknown origin) transduced in mouse BaF3 cells incubated for 48 hrs by Cell Titer Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed