Report error Found 67 Enz. Inhib. hit(s) with all data for entry = 50022160
Affinity DataIC50: 4.20nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Inhibition of NLuc-fused DNMT1 expressed hypomorphic in human HCT-116 cells assessed as TSG repoter activation at 3 uM incubated for 72 hrs by Nano-G...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of HDAC3 (unknown origin) using Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 ...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of HDAC1 (unknown origin) using Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 ...More data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of HDAC extracted from human HeLa cell nucleus using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of HDAC extracted from human HeLa cell nucleus using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of HDAC extracted from human HeLa cell nucleus using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of HDAC extracted from human HeLa cell nucleus using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of HDAC extracted from human HeLa cell nucleus using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of HDAC1 (unknown origin) using Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 ...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of HDAC3 (unknown origin) using Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 ...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC extracted from human HeLa cell nucleus using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of HDAC6 (unknown origin) using Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 ...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of HDAC2 (unknown origin) using Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 ...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of HDAC extracted from human HeLa cell nucleus using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of HDAC extracted from human HeLa cell nucleus using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of HDAC extracted from human HeLa cell nucleus using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of HDAC extracted from human HeLa cell nucleus using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of HDAC extracted from human HeLa cell nucleus using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of HDAC extracted from human HeLa cell nucleus using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of HDAC extracted from human HeLa cell nucleus using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of HDAC extracted from human HeLa cell nucleus using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of HDAC extracted from human HeLa cell nucleus using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of HDAC extracted from human HeLa cell nucleus using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of HDAC extracted from human HeLa cell nucleus using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of HDAC2 (unknown origin) using Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 ...More data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of HDAC extracted from human HeLa cell nucleus using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of HDAC extracted from human HeLa cell nucleus using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of HDAC extracted from human HeLa cell nucleus using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataIC50: 531nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Inhibition of HDAC extracted from human HeLa cell nucleus using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataEC50: 750nMAssay Description:Inhibition of NLuc-fused DNMT1 expressed hypomorphic in human HCT-116 cells assessed as TSG repoter activation at 3 uM incubated for 72 hrs by Nano-G...More data for this Ligand-Target Pair
Affinity DataIC50: 870nMAssay Description:Inhibition of HDAC extracted from human HeLa cell nucleus using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataIC50: 930nMAssay Description:Inhibition of DNMT3A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of HDAC extracted from human HeLa cell nucleus using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataEC50: 1.09E+3nMAssay Description:Inhibition of NLuc-fused DNMT1 expressed hypomorphic in human HCT-116 cells assessed as TSG repoter activation at 3 uM incubated for 72 hrs by Nano-G...More data for this Ligand-Target Pair
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of HDAC extracted from human HeLa cell nucleus using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataEC50: 1.18E+3nMAssay Description:Inhibition of NLuc-fused DNMT1 expressed hypomorphic in human HCT-116 cells assessed as TSG repoter activation at 3 uM incubated for 72 hrs by Nano-G...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of HDAC extracted from human HeLa cell nucleus using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of DNMT3B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of DNMT3A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.02E+3nMAssay Description:Inhibition of DNMT1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.16E+3nMAssay Description:Inhibition of DNMT1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of DNMT3B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.73E+3nMAssay Description:Inhibition of HDAC4 (unknown origin) using Leu-Gly-Lys(TFA)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30...More data for this Ligand-Target Pair









3D Structure (crystal)

















