Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50022164
TargetMAP kinase-activated protein kinase 2(Human)
PI Health Sciences

Curated by ChEMBL
LigandPNGBDBM689029(US20240190890, Compound I-255 | (S)-10-(fluorometh...)
Affinity DataIC50: 1nMAssay Description:Inhibition of MK2 (unknown origin) using ST3-Sox peptide as substrate measured for 120 mins in presence of ATP by Synergy H4 plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
PI Health Sciences

Curated by ChEMBL
LigandPNGBDBM688793(US20240190890, Compound I-13 | (R)-3-(2-(methoxyme...)
Affinity DataIC50: 1nMAssay Description:Inhibition of MK2 (unknown origin) using ST3-Sox peptide as substrate measured for 120 mins in presence of ATP by Synergy H4 plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
PI Health Sciences

Curated by ChEMBL
LigandPNGBDBM688919(US20240190890, Compound I-139 | (R)-10-methyl-3-(6...)
Affinity DataIC50: 2nMAssay Description:Inhibition of MK2 (unknown origin) using ST3-Sox peptide as substrate measured for 120 mins in presence of ATP by Synergy H4 plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
PI Health Sciences

Curated by ChEMBL
LigandPNGBDBM688839(US20240190890, Compound I-59 | (R)-3-(6-ethynyl-2-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of MK2 (unknown origin) using ST3-Sox peptide as substrate measured for 120 mins in presence of ATP by Synergy H4 plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
PI Health Sciences

Curated by ChEMBL
LigandPNGBDBM688985(US20240190890, Compound I-206 | (R)-10-methyl-3-(4...)
Affinity DataIC50: 4nMAssay Description:Inhibition of MK2 (unknown origin) using ST3-Sox peptide as substrate measured for 120 mins in presence of ATP by Synergy H4 plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
PI Health Sciences

Curated by ChEMBL
LigandPNGBDBM688844(US20240190890, Compound I-64 | (R)-3-(2-(3-amino-3...)
Affinity DataIC50: 4nMAssay Description:Inhibition of MK2 (unknown origin) using ST3-Sox peptide as substrate measured for 120 mins in presence of ATP by Synergy H4 plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
PI Health Sciences

Curated by ChEMBL
LigandPNGBDBM688778(US20240190890, Compound I-1 | (R)-3-(2-ethynyl-5-f...)
Affinity DataIC50: 5nMAssay Description:Inhibition of MK2 (unknown origin) using ST3-Sox peptide as substrate measured for 120 mins in presence of ATP by Synergy H4 plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
PI Health Sciences

Curated by ChEMBL
LigandPNGBDBM688896(US20240190890, Compound I-116 | (R)-10-methyl-3-(2...)
Affinity DataIC50: 6nMAssay Description:Inhibition of MK2 (unknown origin) using ST3-Sox peptide as substrate measured for 120 mins in presence of ATP by Synergy H4 plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
PI Health Sciences

Curated by ChEMBL
LigandPNGBDBM688966(US20240190890, Compound I-187 | (R)-3-(2-(((2R,6R)...)
Affinity DataIC50: 8nMAssay Description:Inhibition of MK2 (unknown origin) using ST3-Sox peptide as substrate measured for 120 mins in presence of ATP by Synergy H4 plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
PI Health Sciences

Curated by ChEMBL
LigandPNGBDBM688915(US20240190890, Compound I-135 | (R)-3-(2-(3-amino-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of MK2 (unknown origin) using ST3-Sox peptide as substrate measured for 120 mins in presence of ATP by Synergy H4 plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
PI Health Sciences

Curated by ChEMBL
LigandPNGBDBM688872(US20240190890, Compound I-92 | (R)-3-(5-(difluorom...)
Affinity DataIC50: 17nMAssay Description:Inhibition of MK2 (unknown origin) using ST3-Sox peptide as substrate measured for 120 mins in presence of ATP by Synergy H4 plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
PI Health Sciences

Curated by ChEMBL
LigandPNGBDBM689037(US20240190890, Compound I-263 | (R)-3-(5-((2-oxa-6...)
Affinity DataIC50: 47nMAssay Description:Inhibition of MK2 (unknown origin) using ST3-Sox peptide as substrate measured for 120 mins in presence of ATP by Synergy H4 plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
PI Health Sciences

Curated by ChEMBL
LigandPNGBDBM688806(US20240190890, Compound I-26 | (R)-10-methyl-3-(5-...)
Affinity DataIC50: 684nMAssay Description:Inhibition of MK2 (unknown origin) using ST3-Sox peptide as substrate measured for 120 mins in presence of ATP by Synergy H4 plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
PI Health Sciences

Curated by ChEMBL
LigandPNGBDBM689001(US20240190890, Compound I-223 | (R)-10-methyl-3-(3...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MK2 (unknown origin) using ST3-Sox peptide as substrate measured for 120 mins in presence of ATP by Synergy H4 plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed