Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50022829
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654797BDBM50654797(CHEMBL6120726)
Affinity DataKd:  1.40nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50361557BDBM50361557(CHEMBL1089334)
Affinity DataEC50:  20nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654797BDBM50654797(CHEMBL6120726)
Affinity DataEC50:  30nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654830BDBM50654830(CHEMBL6152937)
Affinity DataIC50: 39nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654818BDBM50654818(CHEMBL6143654)
Affinity DataEC50:  42nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18073BDBM18073(L-[2,3,4,5,6-3H]phenylalanine | (2S)-2-amino-3-phe...)
Affinity DataIC50: 55nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654807BDBM50654807(CHEMBL6147911)
Affinity DataEC50:  92nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654798BDBM50654798(CHEMBL6150751)
Affinity DataEC50:  94nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654796BDBM50654796(CHEMBL6150000)
Affinity DataEC50:  105nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654814BDBM50654814(CHEMBL6102846)
Affinity DataEC50:  134nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654832BDBM50654832(CHEMBL6162470)
Affinity DataIC50: 138nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654813BDBM50654813(CHEMBL6162940)
Affinity DataEC50:  141nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654816BDBM50654816(CHEMBL6120326)
Affinity DataEC50:  146nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654824BDBM50654824(CHEMBL6102298)
Affinity DataEC50:  147nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654819BDBM50654819(CHEMBL6150310)
Affinity DataEC50:  181nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654825BDBM50654825(CHEMBL6146772)
Affinity DataEC50:  205nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654799BDBM50654799(CHEMBL6103118)
Affinity DataEC50:  211nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654820BDBM50654820(CHEMBL6102646)
Affinity DataEC50:  329nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654833BDBM50654833(CHEMBL6114881)
Affinity DataIC50: 341nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654817BDBM50654817(CHEMBL6102773)
Affinity DataEC50:  382nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654823BDBM50654823(CHEMBL6163133)
Affinity DataEC50:  432nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654811BDBM50654811(CHEMBL6151785)
Affinity DataEC50:  435nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654810BDBM50654810(CHEMBL6149741)
Affinity DataEC50:  437nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654808BDBM50654808(CHEMBL6134184)
Affinity DataEC50:  515nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654800BDBM50654800(CHEMBL6142256)
Affinity DataEC50:  531nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654802BDBM50654802(CHEMBL6149843)
Affinity DataEC50:  535nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654815BDBM50654815(CHEMBL6145919)
Affinity DataEC50:  550nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654826BDBM50654826(CHEMBL6144258)
Affinity DataEC50:  552nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654821BDBM50654821(CHEMBL6167242)
Affinity DataEC50:  606nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654809BDBM50654809(CHEMBL6159864)
Affinity DataEC50:  612nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654831BDBM50654831(CHEMBL6134508)
Affinity DataIC50: 616nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654806BDBM50654806(CHEMBL6142016)
Affinity DataEC50:  634nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654805BDBM50654805(CHEMBL6159566)
Affinity DataEC50:  643nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654803BDBM50654803(CHEMBL6160594)
Affinity DataEC50:  648nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654827BDBM50654827(CHEMBL6133822)
Affinity DataEC50:  649nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654829BDBM50654829(CHEMBL6152070)
Affinity DataIC50: 681nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654801BDBM50654801(CHEMBL6162887)
Affinity DataEC50:  703nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654804BDBM50654804(CHEMBL6160801)
Affinity DataEC50:  725nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654828BDBM50654828(CHEMBL6091870)
Affinity DataIC50: 783nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654812BDBM50654812(CHEMBL6159882)
Affinity DataEC50:  796nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654822BDBM50654822(CHEMBL6159964)
Affinity DataEC50:  889nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed