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Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50048685
TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50291785(6,6-Dimethyl-1-(3-m-tolyloxymethyl-phenyl)-1,6-dih...)
Affinity DataKi:  537nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50291795(CHEMBL441503 | {3-[3-(4,6-Diamino-2,2-dimethyl-2H-...)
Affinity DataKi:  646nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50291800(6,6-Dimethyl-1-(3-undecyloxy-phenyl)-1,6-dihydro-[...)
Affinity DataKi:  646nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50405099(CHEMBL33750)
Affinity DataKi:  676nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50405076(CHEMBL269704)
Affinity DataKi:  708nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50405037(CHEMBL33558)
Affinity DataKi:  871nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50291782(3-[3-(4,6-Diamino-2,2-dimethyl-2H-[1,3,5]triazin-1...)
Affinity DataKi:  891nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50405087(CHEMBL7435)
Affinity DataKi:  891nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50291797(6,6-Dimethyl-1-{3-[2-(3-trifluoromethyl-phenoxy)-e...)
Affinity DataKi:  912nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50291783(1-[3-(3-Methoxy-phenoxymethyl)-phenyl]-6,6-dimethy...)
Affinity DataKi:  955nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50291806(1-[3-(Adamantan-1-ylmethoxy)-phenyl]-6,6-dimethyl-...)
Affinity DataKi:  977nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50291789(1-[3-(3-Chloro-phenoxymethyl)-phenyl]-6,6-dimethyl...)
Affinity DataKi:  977nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50291778(CHEMBL20812 | N-{3-[3-(4,6-Diamino-2,2-dimethyl-2H...)
Affinity DataKi:  1.02E+3nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50291802(1-[3-(3-Ethyl-phenoxymethyl)-phenyl]-6,6-dimethyl-...)
Affinity DataKi:  1.12E+3nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50225441(CHEMBL59212)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50291771(CHEMBL20528 | {3-[3-(4,6-Diamino-2,2-dimethyl-2H-[...)
Affinity DataKi:  1.23E+3nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50405069(CHEMBL287235)
Affinity DataKi:  1.32E+3nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50090054(1-(3-Chloro-phenyl)-6,6-dimethyl-1,6-dihydro-[1,3,...)
Affinity DataKi:  1.35E+3nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50291801(6,6-Dimethyl-1-(3-tetradecyloxy-phenyl)-1,6-dihydr...)
Affinity DataKi:  1.41E+3nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50405083(CHEMBL267499)
Affinity DataKi:  1.41E+3nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50405067(CHEMBL32063)
Affinity DataKi:  1.78E+3nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50291793(6,6-Dimethyl-1-(3-trifluoromethyl-phenyl)-1,6-dihy...)
Affinity DataKi:  2.04E+3nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50405089(CHEMBL268414)
Affinity DataKi:  2.63E+3nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50291779(3-(4,6-Diamino-2,2-dimethyl-2H-[1,3,5]triazin-1-yl...)
Affinity DataKi:  3.09E+3nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50405059(CHEMBL7070)
Affinity DataKi:  3.80E+3nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50291780(1-(3-Benzyloxy-phenyl)-6,6-dimethyl-1,6-dihydro-[1...)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50291798(1-(3-tert-Butyl-phenyl)-6,6-dimethyl-1,6-dihydro-[...)
Affinity DataKi:  1.91E+4nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50090067(6,6-Dimethyl-1-phenyl-1,6-dihydro-[1,3,5]triazine-...)
Affinity DataKi:  3.09E+4nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50291776(3-(4,6-Diamino-2,2-dimethyl-2H-[1,3,5]triazin-1-yl...)
Affinity DataKi:  2.04E+5nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50291777(3-(4,6-Diamino-2,2-dimethyl-2H-[1,3,5]triazin-1-yl...)
Affinity DataKi:  3.31E+5nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50405065(CHEMBL286571)
Affinity DataKi:  3.98E+8nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50291794(6,6-Dimethyl-1-(3-phenylsulfanylmethyl-phenyl)-1,6...)
Affinity DataKi:  4.37E+8nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed