Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50023496
TargetCD74-ROS1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50018830BDBM50018830(CHEMBL3286830 | US10543199, Compound PF-06463922 |...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of ROS1/CD74 (unknown origin) expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSLC34A2-ROS1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50018830BDBM50018830(CHEMBL3286830 | US10543199, Compound PF-06463922 |...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of ROS1-SLC34A2 (unknown origin) expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCD74-ROS1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 374727BDBM374727(US10246466, Example 93 | (7S,13R)-11-fluoro-7,13-d...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of ROS1/CD74 (unknown origin) expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSLC34A2-ROS1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 374727BDBM374727(US10246466, Example 93 | (7S,13R)-11-fluoro-7,13-d...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of ROS1-SLC34A2 (unknown origin) expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of ROS1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSLC34A2-ROS1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of ROS1-SLC34A2 (unknown origin) expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCD74-ROS1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of ROS1/CD74 (unknown origin) expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetFocal adhesion kinase 1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase Fer(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of FER (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of CHEK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of FES (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCD74-ROS1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50185140BDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 13nMAssay Description:Inhibition of ROS1/CD74 (unknown origin) expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSLC34A2-ROS1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50185140BDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 23nMAssay Description:Inhibition of ROS1-SLC34A2 (unknown origin) expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 27nMAssay Description:Inhibition of ERBB4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProtein-tyrosine kinase 2-beta(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 34nMAssay Description:Inhibition of PTK2B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 35nMAssay Description:Inhibition of CLK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit delta(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 39nMAssay Description:Inhibition of CAMK2D (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 40nMAssay Description:Inhibition of CHEK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 42nMAssay Description:Inhibition of ERBB2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetInsulin receptor-related protein(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 45nMAssay Description:Inhibition of INSRR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetNUAK family SNF1-like kinase 1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 47nMAssay Description:Inhibition of NUAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit gamma(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 48nMAssay Description:Inhibition of CAMK2G degradation (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436850BDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 50nMAssay Description:Inhibition of ROS1 in human HCC78 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetLeukocyte tyrosine kinase receptor(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 54nMAssay Description:Inhibition of LTK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 69nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProtein-tyrosine kinase 6(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 76nMAssay Description:Inhibition of BRK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 82nMAssay Description:Inhibition of RET (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 95nMAssay Description:Inhibition of C-MET (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 161nMAssay Description:Inhibition of ROS1 G2032R mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Mouse)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436850BDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 180nMAssay Description:Inhibition of ROS1 in mouse Ba/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed