Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50023496
TargetCD74-ROS1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50018830BDBM50018830(CHEMBL3286830 | US10543199, Compound PF-06463922 |...)
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetSLC34A2-ROS1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50018830BDBM50018830(CHEMBL3286830 | US10543199, Compound PF-06463922 |...)
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetCD74-ROS1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 374727BDBM374727(US10246466, Example 93 | (7S,13R)-11-fluoro-7,13-d...)
Affinity DataIC50: 0.700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetSLC34A2-ROS1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 374727BDBM374727(US10246466, Example 93 | (7S,13R)-11-fluoro-7,13-d...)
Affinity DataIC50: 0.800nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 0.800nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetALK tyrosine kinase receptor(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 0.900nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetSLC34A2-ROS1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 1.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetCD74-ROS1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 1.60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetFocal adhesion kinase 1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 2.40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetTyrosine-protein kinase Fer(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 3.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 3.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 3.60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 7.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetCD74-ROS1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50185140BDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetSLC34A2-ROS1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50185140BDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 23nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 27nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetProtein-tyrosine kinase 2-beta(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 34nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetDual specificity protein kinase CLK1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 35nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit delta(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 39nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 42nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetInsulin receptor-related protein(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 45nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetNUAK family SNF1-like kinase 1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 47nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit gamma(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 48nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436850BDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetLeukocyte tyrosine kinase receptor(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 54nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetEpidermal growth factor receptor(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 69nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetProtein-tyrosine kinase 6(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 76nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 82nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetHepatocyte growth factor receptor(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 95nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 161nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Mouse)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436850BDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 180nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed