Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50022832
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654877BDBM50654877(CHEMBL6152165)
Affinity DataIC50: 230nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as decrease in amyloid beta-42 secretion by cell based AlphaLisa assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654875BDBM50654875(CHEMBL6120588)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as decrease in amyloid beta-42 secretion by cell based AlphaLisa assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654874BDBM50654874(CHEMBL6163746)
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as decrease in amyloid beta-42 secretion by cell based AlphaLisa assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654876BDBM50654876(CHEMBL6151367)
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as decrease in amyloid beta-42 secretion by cell based AlphaLisa assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetTopoisomerase IV(Staphylococcus aureus)
Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 246600BDBM246600(DNA topoisomerase inhibitor, 2)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK1 (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 246600BDBM246600(DNA topoisomerase inhibitor, 2)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 17beta-HSD2 in human using MDA-MB-231 cells using [3H]-E2 as substrate after 6 hrs by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetRibonuclease P protein component(Staphylococcus aureus)
Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654878BDBM50654878(CHEMBL6165970)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as decrease in amyloid beta-42 secretion by cell based AlphaLisa assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetTopoisomerase IV(Staphylococcus aureus)
Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654879BDBM50654879(CHEMBL6165974)
Affinity DataIC50: 1.00E+5nMAssay Description:Agonist activity at TLR2 in human cells by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654879BDBM50654879(CHEMBL6165974)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as decrease in amyloid beta-42 secretion by cell based AlphaLisa assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed