Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50022971
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of full-length PDE4D2 (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand Info
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of full-length PDE4D2 (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand Info
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibition of full-length PDE4D2 (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand Info
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of full-length PDE4D2 (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand Info
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of full-length PDE4D2 (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand Info
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of full-length PDE4D2 (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand Info
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of full-length PDE4D2 (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand Info
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of full-length PDE4D2 (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE2A (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition and measured a...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE7A (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition and measured a...More data for this Ligand-Target Pair
Ligand Info
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE5A (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition and measured a...More data for this Ligand-Target Pair
Ligand Info
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE11A (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand Info
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE10A (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE9A (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition and measured a...More data for this Ligand-Target Pair
Ligand Info
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE3A (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition and measured a...More data for this Ligand-Target Pair
Ligand Info
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE1A (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition and measured a...More data for this Ligand-Target Pair
Ligand Info
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE8A (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition and measured a...More data for this Ligand-Target Pair
Ligand Info
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Human)
Guangdong Academy of Sciences
Curated by ChEMBL
Guangdong Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE6C (unknown origin) using FAM-cAMP as substrate preincubated with compound for 15 mins followed by substrate addition and measured a...More data for this Ligand-Target Pair
Ligand Info
