Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50022666
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330063BDBM50330063(1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c...)
Affinity DataEC50:  70nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330062BDBM50330062(1-(3-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c...)
Affinity DataEC50:  110nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241029BDBM50241029(1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...)
Affinity DataEC50:  120nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476153BDBM50476153(CHEMBL6091969)
Affinity DataEC50:  210nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476155BDBM50476155(CHEMBL6092230)
Affinity DataEC50:  350nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476152BDBM50476152(CHEMBL6092110)
Affinity DataEC50:  730nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed
TargetToll-like receptor 8(Human)
Panjab University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330063BDBM50330063(1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c...)
Affinity DataEC50:  1.03E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 8(Human)
Panjab University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330062BDBM50330062(1-(3-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c...)
Affinity DataEC50:  1.70E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 8(Human)
Panjab University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241029BDBM50241029(1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...)
Affinity DataEC50:  2.59E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476154BDBM50476154(CHEMBL6092105)
Affinity DataEC50:  2.83E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476156BDBM50476156(CHEMBL6078205)
Affinity DataEC50:  3.72E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed
TargetToll-like receptor 8(Human)
Panjab University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476153BDBM50476153(CHEMBL6091969)
Affinity DataEC50:  4.99E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476151BDBM50476151(CHEMBL6092045)
Affinity DataEC50:  1.17E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed