Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50022753
TargetTyrosine-protein kinase JAK2(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653919BDBM50653919(CHEMBL6150030)
Affinity DataIC50: 0.490nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetTyrosine-protein kinase JAK2(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653917BDBM50653917(CHEMBL6134634)
Affinity DataIC50: 0.720nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653919BDBM50653919(CHEMBL6150030)
Affinity DataIC50: 2.60nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653917BDBM50653917(CHEMBL6134634)
Affinity DataIC50: 4.40nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetTyrosine-protein kinase JAK3(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653919BDBM50653919(CHEMBL6150030)
Affinity DataIC50: 5.60nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetTyrosine-protein kinase JAK3(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653917BDBM50653917(CHEMBL6134634)
Affinity DataIC50: 7.90nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetTyrosine-protein kinase JAK1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653919BDBM50653919(CHEMBL6150030)
Affinity DataIC50: 8.30nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 6(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653919BDBM50653919(CHEMBL6150030)
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetTyrosine-protein kinase JAK1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653917BDBM50653917(CHEMBL6134634)
Affinity DataIC50: 14nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653918BDBM50653918(CHEMBL6147319)
Affinity DataIC50: 22nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653919BDBM50653919(CHEMBL6150030)
Affinity DataIC50: 38nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311017BDBM50311017(N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyri...)
Affinity DataIC50: 40nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 6(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653917BDBM50653917(CHEMBL6134634)
Affinity DataIC50: 45nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653916BDBM50653916(CHEMBL6103352)
Affinity DataIC50: 46nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653915BDBM50653915(CHEMBL6134447)
Affinity DataIC50: 51nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 2(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653919BDBM50653919(CHEMBL6150030)
Affinity DataIC50: 89nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653917BDBM50653917(CHEMBL6134634)
Affinity DataIC50: 98nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 3(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653919BDBM50653919(CHEMBL6150030)
Affinity DataIC50: 105nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653913BDBM50653913(CHEMBL6101879)
Affinity DataIC50: 130nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653914BDBM50653914(CHEMBL6103471)
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 3(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653917BDBM50653917(CHEMBL6134634)
Affinity DataIC50: 161nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653925BDBM50653925(CHEMBL6102445)
Affinity DataIC50: 180nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653912BDBM50653912(CHEMBL6161291)
Affinity DataIC50: 220nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 2(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653917BDBM50653917(CHEMBL6134634)
Affinity DataIC50: 290nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653923BDBM50653923(CHEMBL6152078)
Affinity DataIC50: 440nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653922BDBM50653922(CHEMBL6141695)
Affinity DataIC50: 680nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653921BDBM50653921(CHEMBL6102243)
Affinity DataIC50: 780nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653920BDBM50653920(CHEMBL6162430)
Affinity DataIC50: 970nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 8(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653919BDBM50653919(CHEMBL6150030)
Affinity DataIC50: 989nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 8(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653917BDBM50653917(CHEMBL6134634)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653909BDBM50653909(CHEMBL6120541)
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653926BDBM50653926(CHEMBL6145556)
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653910BDBM50653910(CHEMBL6142150)
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653911BDBM50653911(CHEMBL6142836)
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHistone deacetylase 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653924BDBM50653924(CHEMBL6145722)
Affinity DataIC50: 2.80E+4nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed