Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50023008
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 738792BDBM738792(US20250145632, Example Z7)
Affinity DataKd:  0.0600nMAssay Description:Binding affinity to CDK7/CyclinH (unknown origin) assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583929BDBM50583929(Sy 5609 | Sy-5609 | SY5609 | SY-5609)
Affinity DataKd:  0.110nMAssay Description:Binding affinity to CDK7/CyclinH (unknown origin) assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657729BDBM50657729(CHEMBL6143916)
Affinity DataKd:  0.120nMAssay Description:Binding affinity to CDK7/CyclinH (unknown origin) assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657727BDBM50657727(CHEMBL6152747)
Affinity DataKd:  0.140nMAssay Description:Binding affinity to CDK7/CyclinH (unknown origin) assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 738791BDBM738791(US20250145632, Example Z5)
Affinity DataKd:  0.160nMAssay Description:Binding affinity to CDK7/CyclinH (unknown origin) assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataKd:  0.180nMAssay Description:Binding affinity to CDK7/CyclinH (unknown origin) assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50583929BDBM50583929(Sy 5609 | Sy-5609 | SY5609 | SY-5609)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of CDK7/CyclinH/MAT1 (unknown origin) in presence of ATP by kinase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetCyclin-Y/Cyclin-dependent kinase 16(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of CDK16/CyclinY (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657728BDBM50657728(CHEMBL6161045)
Affinity DataKd:  3.5nMAssay Description:Binding affinity to CDK7/CyclinH (unknown origin) assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 18(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of CDK18/Cyclin Y (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50657727BDBM50657727(CHEMBL6152747)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of CDK7/CyclinH/MAT1 (unknown origin) in presence of ATP by kinase activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase D3(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of PRKD3 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetMitogen-activated protein kinase 15(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of Erk8 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50657726BDBM50657726(CHEMBL6120432)
Affinity DataIC50: 11nMAssay Description:Inhibition of CDK7/CyclinH/MAT1 (unknown origin) in presence of ATP by kinase activity assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 13nMAssay Description:Inhibition of CDK4/Cyclin D3 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetCyclin-Y(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 16nMAssay Description:Inhibition of CDK14/Cyclin Y (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase D1(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 24nMAssay Description:Inhibition of PRKD1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetMitogen-activated protein kinase 7(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 27nMAssay Description:Inhibition of Erk5 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 30nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase D2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 45nMAssay Description:Inhibition of PRKD2 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHomeodomain-interacting protein kinase 4(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 55nMAssay Description:Inhibition of HIPK4 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 62nMAssay Description:Inhibition of CDK12 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 146nMAssay Description:Inhibition of CDK4/CyclinD1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 9(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 258nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 292nMAssay Description:Inhibition of RSK2 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase ULK1(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 368nMAssay Description:Inhibition of ULK1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase TAO1(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 546nMAssay Description:Inhibition of TAOK1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed