Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50022888
TargetCyclic GMP-AMP synthase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582657BDBM50582657(CHEMBL5082056 | US20250179079, Comparative Example...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of cGAS in dsDNA-stimulated human THP-1 cells assessed as cGAMP formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetCyclic GMP-AMP synthase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582698BDBM50582698(CHEMBL4448176 | US12522603, Compound TDI-008087)
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of cGAS in dsDNA-stimulated human THP-1 cells assessed as cGAMP formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetCyclic GMP-AMP synthase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655720BDBM50655720(CHEMBL6150103)
Affinity DataIC50: 2.95E+3nMAssay Description:Inhibition of cGAS in dsDNA-stimulated human THP-1 cells assessed as cGAMP formationMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed