Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50022763
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654016BDBM50654016(CHEMBL6151956)
Affinity DataKd:  2nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of fMLP-induced neutrophil migration assay by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617569BDBM50617569(CHEMBL5418436)
Affinity DataKd:  30nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of C5a-induced AKT phosphorylation at Ser473 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654022BDBM50654022(CHEMBL6132727)
Affinity DataKd:  36nMAssay Description:Inhibition of Nav1.7 by cell-based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654021BDBM50654021(CHEMBL6143618)
Affinity DataIC50: 40nMAssay Description:Inhibition of Nav1.7 by cell-based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654020BDBM50654020(CHEMBL6102987)
Affinity DataIC50: 121nMAssay Description:Inhibition of Nav1.7 by cell-based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50529556BDBM50529556(CHEMBL4552313)
Affinity DataKd:  129nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of C5a-induced AKT phosphorylation at Ser473 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654020BDBM50654020(CHEMBL6102987)
Affinity DataKd:  144nMAssay Description:Inhibition of Nav1.7 by cell-based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654018BDBM50654018(CHEMBL6114900)
Affinity DataIC50: 163nMAssay Description:Inhibition of human DPP9 using GLY-Pro-MCA as substrate after 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654019BDBM50654019(CHEMBL6141635)
Affinity DataIC50: 264nMAssay Description:Inhibition of Nav1.7 by cell-based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654020BDBM50654020(CHEMBL6102987)
Affinity DataIC50: 500nMAssay Description:Inhibition of Tau phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654019BDBM50654019(CHEMBL6141635)
Affinity DataKd:  565nMAssay Description:Inhibition of human mPGES-1 assessed as production of PGE2 by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654017BDBM50654017(CHEMBL6149142)
Affinity DataKd:  645nMAssay Description:Inhibition of Nav1.7 by cell-based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50566867BDBM50566867(CHEMBL4855926)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of fMLP-induced neutrophil migration assay by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654017BDBM50654017(CHEMBL6149142)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human DPP9 using GLY-Pro-MCA as substrate after 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50566879BDBM50566879(CHEMBL4851720)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of human DPP9 using GLY-Pro-MCA as substrate after 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50566878BDBM50566878(CHEMBL4868961)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of human DPP8 using GLY-Pro-MCA as substrate after 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654018BDBM50654018(CHEMBL6114900)
Affinity DataKd:  1.34E+3nMAssay Description:Inhibition of human mPGES-1 assessed as production of PGE2 by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654019BDBM50654019(CHEMBL6141635)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of Tau phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654017BDBM50654017(CHEMBL6149142)
Affinity DataIC50: 2.02E+3nMAssay Description:Inhibition of human mPGES-1 assessed as production of PGE2 by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654018BDBM50654018(CHEMBL6114900)
Affinity DataIC50: 2.36E+3nMAssay Description:Inhibition of Tau phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50566881BDBM50566881(CHEMBL4874295)
Affinity DataIC50: 3.26E+3nMAssay Description:Inhibition of human DPP8 using GLY-Pro-MCA as substrate after 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50566890BDBM50566890(CHEMBL4865432)
Affinity DataIC50: 3.46E+3nMAssay Description:Inhibition of human DPP9 using GLY-Pro-MCA as substrate after 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50566879BDBM50566879(CHEMBL4851720)
Affinity DataIC50: 4.29E+3nMAssay Description:Inhibition of human DPP8 using GLY-Pro-MCA as substrate after 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654021BDBM50654021(CHEMBL6143618)
Affinity DataIC50: 5.67E+3nMAssay Description:Inhibition of human NPM-ALK phosphorylation using 4-MeUP substrate by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50566880BDBM50566880(CHEMBL4873290)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human DPP8 using GLY-Pro-MCA as substrate after 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50566874BDBM50566874(CHEMBL4850693)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of fMLP-induced neutrophil migration assay by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50566873BDBM50566873(CHEMBL4859531)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of fMLP-induced neutrophil migration assay by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50566877BDBM50566877(CHEMBL4863719)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human DPP9 using GLY-Pro-MCA as substrate after 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetProtein ENL(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50566875BDBM50566875(CHEMBL4869424)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human DPP8 using GLY-Pro-MCA as substrate after 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed