Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50023515
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Wuyi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14774BDBM14774(DAXAS | 3-(cyclopropylmethoxy)-N-(3,5-dichloropyri...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PDE4D3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Wuyi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 589740BDBM589740(US11559538, Example 4 | US20240083921, Compound A)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of PDE4B2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Wuyi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664656BDBM50664656(CHEMBL6149505)
Affinity DataIC50: 0.570nMAssay Description:Inhibition of recombinant full-length PDE4D2 (unknown origin) using FAM-cAMP as substrate preincubated for 15 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Wuyi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664656BDBM50664656(CHEMBL6149505)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of PDE4B (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Wuyi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 150200BDBM150200(US8980905, 108 | US9637499, Compound 108)
Affinity DataIC50: 3nMAssay Description:Inhibition of PDE4D (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Wuyi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664656BDBM50664656(CHEMBL6149505)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of PDE4A (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Wuyi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664652BDBM50664652(CHEMBL6172619)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of recombinant full-length PDE4D2 (unknown origin) using FAM-cAMP as substrate preincubated for 15 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Wuyi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664654BDBM50664654(CHEMBL6173226)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant full-length PDE4D2 (unknown origin) using FAM-cAMP as substrate preincubated for 15 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Wuyi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664655BDBM50664655(CHEMBL6142335)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant full-length PDE4D2 (unknown origin) using FAM-cAMP as substrate preincubated for 15 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Wuyi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664653BDBM50664653(CHEMBL6163411)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant full-length PDE4D2 (unknown origin) using FAM-cAMP as substrate preincubated for 15 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Wuyi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248919BDBM50248919((S)-N-(2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsu...)
Affinity DataIC50: 74nMAssay Description:Inhibition of PDE4D (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Wuyi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664657BDBM50664657(CHEMBL6152067)
Affinity DataIC50: 77nMAssay Description:Inhibition of recombinant full-length PDE4D2 (unknown origin) using FAM-cAMP as substrate preincubated for 15 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Wuyi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664656BDBM50664656(CHEMBL6149505)
Affinity DataIC50: 110nMAssay Description:Inhibition of PDE4C (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Wuyi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659304BDBM50659304(Mufemilast | HEMAY-005 | HEMAY005)
Affinity DataIC50: 114nMAssay Description:Inhibition of PDE4D (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Wuyi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277665BDBM50277665(4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yl...)
Affinity DataIC50: 170nMAssay Description:Inhibition of PDE4D7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Wuyi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664651BDBM50664651(CHEMBL6170103)
Affinity DataIC50: 546nMAssay Description:Inhibition of recombinant full-length PDE4D2 (unknown origin) using FAM-cAMP as substrate preincubated for 15 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Wuyi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664650BDBM50664650(CHEMBL6173241)
Affinity DataIC50: 558nMAssay Description:Inhibition of recombinant full-length PDE4D2 (unknown origin) using FAM-cAMP as substrate preincubated for 15 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50664656BDBM50664656(CHEMBL6149505)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE7A (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Wuyi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664656BDBM50664656(CHEMBL6149505)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE3A (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Wuyi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664656BDBM50664656(CHEMBL6149505)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE5A (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50664656BDBM50664656(CHEMBL6149505)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE6C (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50664656BDBM50664656(CHEMBL6149505)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE1A (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Wuyi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664656BDBM50664656(CHEMBL6149505)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE2A (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50664656BDBM50664656(CHEMBL6149505)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE8A (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50664656BDBM50664656(CHEMBL6149505)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE9A (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50664656BDBM50664656(CHEMBL6149505)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Wuyi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664656BDBM50664656(CHEMBL6149505)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE11A (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed