Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50023020
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26658BDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human PTP1B extracted from Escherichia coli BL21 TB1 using p-nitro-phenyl phosphate as substrate assessed as substrate hydrolysis by me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657886BDBM50657886(CHEMBL6162719)
Affinity DataIC50: 18nMAssay Description:Inhibition of male Wistar rat lens ALR2 using D,L-glyceraldehyde as substrate assessed as NADPH consumption by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26658BDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-...)
Affinity DataIC50: 19nMAssay Description:Inhibition of TCPTP (unknown origin) extracted from Escherichia coli BL21 TB1 using p-nitro-phenyl phosphate as substrate assessed as substrate hydro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657885BDBM50657885(CHEMBL6161147)
Affinity DataIC50: 26nMAssay Description:Inhibition of male Wistar rat lens ALR2 using D,L-glyceraldehyde as substrate assessed as NADPH consumption by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126780BDBM50126780(Cyano-[5-fluoro-1-(4-methyl-benzyl)-2-oxo-2,3-dihy...)
Affinity DataIC50: 42nMAssay Description:Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate preincubated for 10 mins in presence of NADPH followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657887BDBM50657887(CHEMBL6152900)
Affinity DataIC50: 187nMAssay Description:Inhibition of male Wistar rat lens ALR2 using D,L-glyceraldehyde as substrate assessed as NADPH consumption by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049730BDBM50049730(Epalrestat | 2-(5-(2-methyl-3-phenylallylidene)-4-...)
Affinity DataIC50: 240nMAssay Description:Inhibition of rat lens ALR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049730BDBM50049730(Epalrestat | 2-(5-(2-methyl-3-phenylallylidene)-4-...)
Affinity DataIC50: 250nMAssay Description:Inhibition of male Wistar rat lens ALR2 using D,L-glyceraldehyde as substrate assessed as NADPH consumption by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657888BDBM50657888(CHEMBL6152690)
Affinity DataIC50: 289nMAssay Description:Inhibition of male Wistar rat lens ALR2 using D,L-glyceraldehyde as substrate assessed as NADPH consumption by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member A1(Rat)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049730BDBM50049730(Epalrestat | 2-(5-(2-methyl-3-phenylallylidene)-4-...)
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of rat kidney ALR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member A1(Rat)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049730BDBM50049730(Epalrestat | 2-(5-(2-methyl-3-phenylallylidene)-4-...)
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of male Wistar rat kidney ALR1 using D-glucuronate as substrate assessed as NADPH consumption by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member A1(Rat)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657885BDBM50657885(CHEMBL6161147)
Affinity DataIC50: 7.54E+3nMAssay Description:Inhibition of male Wistar rat kidney ALR1 using D-glucuronate as substrate assessed as NADPH consumption by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member A1(Rat)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657886BDBM50657886(CHEMBL6162719)
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of male Wistar rat kidney ALR1 using D-glucuronate as substrate assessed as NADPH consumption by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member A1(Rat)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657888BDBM50657888(CHEMBL6152690)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of male Wistar rat kidney ALR1 using D-glucuronate as substrate assessed as NADPH consumption by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member A1(Rat)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657887BDBM50657887(CHEMBL6152900)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of male Wistar rat kidney ALR1 using D-glucuronate as substrate assessed as NADPH consumption by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657888BDBM50657888(CHEMBL6152690)
Affinity DataIC50: 2.13E+4nMAssay Description:Inhibition of polyhis-tagged recombinant human PTP1B (1 to 303 residues) extracted from Escherichia coli BL21 (DE3) pLysS using p-nitro-phenyl phosph...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657888BDBM50657888(CHEMBL6152690)
Affinity DataIC50: 3.78E+4nMAssay Description:Inhibition of polyHis-tagged recombinant human TCPTP (1 to 415 residues) extracted from Escherichia coli BL21 (DE3) pLysS using p-nitro-phenyl phosph...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657885BDBM50657885(CHEMBL6161147)
Affinity DataIC50: 4.28E+4nMAssay Description:Inhibition of polyhis-tagged recombinant human PTP1B (1 to 303 residues) extracted from Escherichia coli BL21 (DE3) pLysS using p-nitro-phenyl phosph...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657885BDBM50657885(CHEMBL6161147)
Affinity DataIC50: 4.71E+4nMAssay Description:Inhibition of polyHis-tagged recombinant human TCPTP (1 to 415 residues) extracted from Escherichia coli BL21 (DE3) pLysS using p-nitro-phenyl phosph...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657887BDBM50657887(CHEMBL6152900)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of polyhis-tagged recombinant human PTP1B (1 to 303 residues) extracted from Escherichia coli BL21 (DE3) pLysS using p-nitro-phenyl phosph...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed