Report error Found 71 Enz. Inhib. hit(s) with all data for entry = 50023521
Affinity DataKi: 0.660nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 3nMAssay Description:Partial agonist activity at recombinant wild-type human GluN1/2C expressed in Xenopus laevis oocytes by TEVC recording methodMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 4.90nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 5nMAssay Description:Antagonist activity at recombinant human GluN1/2B expressed in Xenopus laevis oocytes in presence of glycine/glutamate by TEVC recording methodMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 7nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 8nMAssay Description:Antagonist activity at recombinant human GluN1/2A expressed in Xenopus laevis oocytes in presence of glycine/glutamate by TEVC recording methodMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 10nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 11nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 15nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 16nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 16nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 19nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 19nMAssay Description:Antagonist activity at recombinant human GluN1/2C expressed in Xenopus laevis oocytes in presence of glycine/glutamate by TEVC recording methodMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 21nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 25nMAssay Description:Partial agonist activity at recombinant wild-type human GluN1/2D expressed in Xenopus laevis oocytes by TEVC recording methodMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 25nMAssay Description:Partial agonist activity at recombinant wild-type human GluN1/2B expressed in Xenopus laevis oocytes by TEVC recording methodMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 25nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 29nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 35nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 41nMAssay Description:Antagonist activity at recombinant human GluN1/2D expressed in Xenopus laevis oocytes in presence of glycine/glutamate by TEVC recording methodMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 64nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 66nMAssay Description:Partial agonist activity at recombinant wild-type human GluN1/2A expressed in Xenopus laevis oocytes by TEVC recording methodMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 71nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 78nMAssay Description:Agonist activity at recombinant human GluN1/2B expressed in Xenopus laevis oocytes by TEVC recording methodMore data for this Ligand-Target Pair
Affinity DataKi: 82nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 96nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 110nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 110nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 110nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 120nMAssay Description:Agonist activity at recombinant human GluN1/2C expressed in Xenopus laevis oocytes by TEVC recording methodMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 140nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 180nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 190nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 220nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 220nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 240nMAssay Description:Agonist activity at recombinant human GluN1/2A expressed in Xenopus laevis oocytes by TEVC recording methodMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 310nMAssay Description:Agonist activity at recombinant human GluN1/2B expressed in Xenopus laevis oocytes by TEVC recording methodMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 330nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 360nMAssay Description:Agonist activity at recombinant human GluN1/2C expressed in Xenopus laevis oocytes by TEVC recording methodMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 450nMAssay Description:Agonist activity at recombinant human GluN1/2D expressed in Xenopus laevis oocytes by TEVC recording methodMore data for this Ligand-Target Pair
Affinity DataEC50: 470nMAssay Description:Agonist activity at recombinant human GluN1/2A expressed in Xenopus laevis oocytes by TEVC recording methodMore data for this Ligand-Target Pair
Affinity DataEC50: 530nMAssay Description:Agonist activity at recombinant human GluN1/2D expressed in Xenopus laevis oocytes by TEVC recording methodMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 660nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 690nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 750nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info



















3D Structure (crystal)














