Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50022710
TargetKappa-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653316BDBM50653316(CHEMBL6146975)
Affinity DataKi:  0.0870nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653315BDBM50653315(CHEMBL6133333)
Affinity DataKi:  0.360nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653316BDBM50653316(CHEMBL6146975)
Affinity DataKi:  1nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653315BDBM50653315(CHEMBL6133333)
Affinity DataKi:  1nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50292340BDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataKi:  166nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653315BDBM50653315(CHEMBL6133333)
Affinity DataKi:  210nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653316BDBM50653316(CHEMBL6146975)
Affinity DataKi:  384nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653315BDBM50653315(CHEMBL6133333)
Affinity DataKi:  721nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetAlpha-2A adrenergic receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653316BDBM50653316(CHEMBL6146975)
Affinity DataKi:  732nMAssay Description:Displacement of radioligand from human recombinant adenosine A2B receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653316BDBM50653316(CHEMBL6146975)
Affinity DataKi:  767nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653316BDBM50653316(CHEMBL6146975)
Affinity DataKi:  829nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetAlpha-1A adrenergic receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653316BDBM50653316(CHEMBL6146975)
Affinity DataKi:  883nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetAlpha-1A adrenergic receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653315BDBM50653315(CHEMBL6133333)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetAlpha-1D adrenergic receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653316BDBM50653316(CHEMBL6146975)
Affinity DataKi:  1.14E+3nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetAlpha-2B adrenergic receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50292340BDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataKi:  1.21E+3nMAssay Description:Displacement of radioligand from human recombinant adenosine A2B receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetAlpha-2B adrenergic receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653315BDBM50653315(CHEMBL6133333)
Affinity DataKi:  1.25E+3nMAssay Description:Displacement of radioligand from human recombinant adenosine A2B receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653316BDBM50653316(CHEMBL6146975)
Affinity DataKi:  1.39E+3nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50292340BDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataKi:  1.41E+3nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653315BDBM50653315(CHEMBL6133333)
Affinity DataKi:  1.52E+3nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653315BDBM50653315(CHEMBL6133333)
Affinity DataKi:  1.79E+3nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetAlpha-1B adrenergic receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653316BDBM50653316(CHEMBL6146975)
Affinity DataKi:  2.02E+3nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653316BDBM50653316(CHEMBL6146975)
Affinity DataKi:  2.31E+3nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetAlpha-2C adrenergic receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653316BDBM50653316(CHEMBL6146975)
Affinity DataKi:  2.86E+3nMAssay Description:Inhibition of Akt2 by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetAlpha-1B adrenergic receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653315BDBM50653315(CHEMBL6133333)
Affinity DataKi:  2.88E+3nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetAlpha-2C adrenergic receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653315BDBM50653315(CHEMBL6133333)
Affinity DataKi:  2.91E+3nMAssay Description:Displacement of radioligand from human recombinant adenosine A2B receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50292340BDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataKi:  2.93E+3nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653316BDBM50653316(CHEMBL6146975)
Affinity DataKi:  3.44E+3nMAssay Description:Inhibition of Akt2 by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetMu-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653316BDBM50653316(CHEMBL6146975)
Affinity DataKi:  3.60E+3nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetMu-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50292340BDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataKi:  3.73E+3nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetAlpha-2C adrenergic receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50292340BDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataKi:  4.79E+3nMAssay Description:Displacement of radioligand from human recombinant adenosine A2B receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50292340BDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataKi:  4.82E+3nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50292340BDBM50292340(CHEMBL508955 | AKUAMMICINE)
Affinity DataKi:  5.49E+3nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetMu-type opioid receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653315BDBM50653315(CHEMBL6133333)
Affinity DataKi:  5.50E+3nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetAlpha-2A adrenergic receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653315BDBM50653315(CHEMBL6133333)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of radioligand from human recombinant adenosine A2B receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed