Report error Found 72 Enz. Inhib. hit(s) with all data for entry = 50022770
Affinity DataKi: 0.0660nMAssay Description:Agonist activity at GAL4-fused PPARalpha assessed as transcriptional activity by cell based assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Agonist activity at GAL4-fused PPARgamma assessed as transcriptional activity by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.640nMAssay Description:Agonist activity at GAL4-fused PPARgamma assessed as transcriptional activity by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.800nMAssay Description:Negative allosteric modulation of mGlu3 assessed as thallium flux through GIRK channels by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.800nMAssay Description:Negative allosteric modulation of mGlu3 assessed as thallium flux through GIRK channels by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 2.5nMAssay Description:Negative allosteric modulation of mGlu3 assessed as thallium flux through GIRK channels by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 3.10nMAssay Description:Inhibition of Cav1.2 assessed as inhibition of calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 3.10nMAssay Description:Antagonist activity at ghrelin receptor assessed as inhibition of ghrelin-induced Ca2+ release by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 5.30nMAssay Description:Negative allosteric modulation of mGlu3 assessed as thallium flux through GIRK channels by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 5.80nMAssay Description:Agonist activity at GAL4-fused PPARgamma assessed as transcriptional activity by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 12nMAssay Description:Antagonist activity at human P2X3 receptor by cell-based calcium influx assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 13nMAssay Description:Agonist activity at GAL4-fused PPARgamma assessed as transcriptional activity by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 13nMAssay Description:Negative allosteric modulation of mGlu3 assessed as thallium flux through GIRK channels by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 13nMAssay Description:Agonist activity at GAL4-fused PPARgamma assessed as transcriptional activity by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 17nMAssay Description:Negative allosteric modulation of mGlu3 assessed as inhibition of glutamate-induced calcium mobilization in presence of Galpha15 by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 23nMAssay Description:Agonist activity at GAL4-fused PPARgamma assessed as transcriptional activity by cell based assayMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Negative allosteric modulation of mGlu3 assessed as thallium flux through GIRK channels by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 33nMAssay Description:Agonist activity at ghrelin receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 44nMAssay Description:Negative allosteric modulation of rat mGlu3 assessed as assessed as thallium flux through GIRK channels by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
TargetTransient receptor potential cation channel subfamily M member 8(Rat)
University Health Network
Curated by ChEMBL
University Health Network
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Agonist activity at GAL4-fused PPARalpha assessed as transcriptional activity by cell based assayMore data for this Ligand-Target Pair
Affinity DataKi: 67nMAssay Description:Negative allosteric modulation of mGlu3 assessed as thallium flux through GIRK channels by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 77nMAssay Description:Antagonist activity at human P2X3 receptor by cell-based calcium influx assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 101nMAssay Description:Negative allosteric modulation of mGlu2 by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
University Health Network
Curated by ChEMBL
University Health Network
Curated by ChEMBL
Affinity DataEC50: 110nMAssay Description:Agonist activity at GAL4-fused PPARalpha assessed as transcriptional activity by cell based assayMore data for this Ligand-Target Pair
Affinity DataKi: 121nMAssay Description:Agonist activity at GAL4-fused PPARgamma assessed as transcriptional activity by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 156nMAssay Description:Agonist activity at GAL4-fused PPARgamma assessed as transcriptional activity by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 203nMAssay Description:Negative allosteric modulation of mGlu3 assessed as thallium flux through GIRK channels by cell-based assayMore data for this Ligand-Target Pair
Affinity DataKi: 211nMAssay Description:Negative allosteric modulation of mGlu5 assessed as inhibition of glutamate-induced calcium mobilization by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 250nMAssay Description:Agonist activity at GAL4-fused PPARalpha assessed as transcriptional activity by cell based assayMore data for this Ligand-Target Pair
Affinity DataKi: 259nMAssay Description:Agonist activity at ghrelin receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 294nMAssay Description:Inhibition of VEGFR2 by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 313nMAssay Description:Agonist activity at GAL4-fused PPARgamma assessed as transcriptional activity by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 345nMAssay Description:Agonist activity at GPR119 receptor by cell based cAMP assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 375nMAssay Description:Negative allosteric modulation of mGlu3 assessed as thallium flux through GIRK channels by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 445nMAssay Description:Agonist activity at GAL4-fused PPARalpha assessed as transcriptional activity by cell based assayMore data for this Ligand-Target Pair
Affinity DataKi: 538nMAssay Description:Agonist activity at ghrelin receptor by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 574nMAssay Description:Agonist activity at GAL4-fused PPARgamma assessed as transcriptional activity by cell based assayMore data for this Ligand-Target Pair
Affinity DataKi: 671nMAssay Description:Positive allosteric modulation of mGlu5 assessed as potentiation of glutamate-induced calcium mobilization by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 842nMAssay Description:Negative allosteric modulation of mGlu3 by cell-based assayMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Negative allosteric modulation of mGlu3 assessed as thallium flux through GIRK channels by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: >1.00E+3nMAssay Description:Antagonist activity at human P2X3 receptor by cell-based calcium influx assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: >1.00E+3nMAssay Description:Negative allosteric modulation of mGlu3 assessed as thallium flux through GIRK channels by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: >1.00E+3nMAssay Description:Antagonist activity at human P2X3 receptor by cell-based calcium influx assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: >1.00E+3nMAssay Description:Negative allosteric modulation of mGlu3 assessed as thallium flux through GIRK channels by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: >1.00E+3nMAssay Description:Negative allosteric modulation of mGlu3 assessed as thallium flux through GIRK channels by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
TargetTransient receptor potential cation channel subfamily V member 1(Human)
University Health Network
Curated by ChEMBL
University Health Network
Curated by ChEMBL
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at GAL4-fused PPARalpha assessed as transcriptional activity by cell based assayMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Negative allosteric modulation of mGlu2 assessed as thallium flux through GIRK channels by cell-based assayMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Agonist activity at GAL4-fused PPARgamma assessed as transcriptional activity by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: >1.00E+3nMAssay Description:Negative allosteric modulation of mGlu3 assessed as thallium flux through GIRK channels by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: >1.00E+3nMAssay Description:Agonist activity at GAL4-fused PPARgamma assessed as transcriptional activity by cell based assayMore data for this Ligand-Target Pair
Ligand Info













3D Structure (crystal)












