Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50022774
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654183BDBM50654183(CHEMBL6103021)
Affinity DataIC50: 3nMAssay Description:Inhibition of Nav1.5 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238854BDBM50238854(CHEBI:58987 | Revatio | Sildenafil Citrate | UK-92...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Nav1.7 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654182BDBM50654182(CHEMBL6160714)
Affinity DataIC50: 5nMAssay Description:Inhibition of Nav1.5 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654184BDBM50654184(CHEMBL6120652)
Affinity DataIC50: 8nMAssay Description:Inhibition of Nav1.5 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617902BDBM50617902(CHEMBL5430448)
Affinity DataIC50: 10nMAssay Description:Inhibition of Nav1.5 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654176BDBM50654176(CHEMBL6148537)
Affinity DataIC50: 11nMAssay Description:Inhibition of Nav1.5 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654174BDBM50654174(CHEMBL6120476)
Affinity DataIC50: 20nMAssay Description:Inhibition of Nav1.5 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654175BDBM50654175(CHEMBL6143714)
Affinity DataIC50: 20nMAssay Description:Inhibition of Nav1.5 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654183BDBM50654183(CHEMBL6103021)
Affinity DataIC50: 20nMAssay Description:Inhibition of Nav1.7 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654173BDBM50654173(CHEMBL6144223)
Affinity DataIC50: 30nMAssay Description:Inhibition of Nav1.5 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654181BDBM50654181(CHEMBL6151306)
Affinity DataIC50: 34nMAssay Description:Inhibition of Nav1.5 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654180BDBM50654180(CHEMBL6148578)
Affinity DataIC50: 39nMAssay Description:Inhibition of Nav1.5 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654177BDBM50654177(CHEMBL6133703)
Affinity DataIC50: 55nMAssay Description:Inhibition of Nav1.5 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654178BDBM50654178(CHEMBL6150032)
Affinity DataIC50: 73nMAssay Description:Inhibition of Nav1.5 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654179BDBM50654179(CHEMBL6150621)
Affinity DataIC50: 198nMAssay Description:Inhibition of Nav1.5 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617903BDBM50617903(CHEMBL5415102)
Affinity DataIC50: 291nMAssay Description:Inhibition of Nav1.5 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617901BDBM50617901(CHEMBL5418520)
Affinity DataIC50: 578nMAssay Description:Inhibition of Nav1.5 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617915BDBM50617915(CHEMBL5395569)
Affinity DataIC50: 2.18E+3nMAssay Description:Inhibition of Nav1.7 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654183BDBM50654183(CHEMBL6103021)
Affinity DataIC50: 3.38E+3nMAssay Description:Inhibition of Nav1.7 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50654183BDBM50654183(CHEMBL6103021)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of Nav1.7 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654183BDBM50654183(CHEMBL6103021)
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of Nav1.7 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654183BDBM50654183(CHEMBL6103021)
Affinity DataIC50: 2.57E+4nMAssay Description:Inhibition of Nav1.7 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654183BDBM50654183(CHEMBL6103021)
Affinity DataIC50: 5.33E+4nMAssay Description:Inhibition of Nav1.7 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654183BDBM50654183(CHEMBL6103021)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Nav1.7 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654183BDBM50654183(CHEMBL6103021)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Nav1.7 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50654183BDBM50654183(CHEMBL6103021)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Nav1.7 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654183BDBM50654183(CHEMBL6103021)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Nav1.7 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed