Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50022783
LigandChemical structure of BindingDB Monomer ID 606098BDBM606098(US11684616, Example 1)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 606122BDBM606122(US11684616, Example 24 | 4-[(1$#958;)-1- aminoethy...)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 519601BDBM519601(US11142525, Example 17)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as reduction in amyloid beta (1 to 42) production by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 606204BDBM606204(US11684616, Example 210 | 4-[(methyl- amino)methyl...)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 606195BDBM606195(US11684616, Example 201)
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 519653BDBM519653(US11142525, Example 55)
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 606199BDBM606199(US11684616, Example 205 | 2-{6-[(5R)-5- (fluoromet...)
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 606178BDBM606178(US11684616, Example 140 | 4-[(1R)-1- aminopropyl]-...)
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 519662BDBM519662(US11142525, Example 63)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 519585BDBM519585(US11142525, Example 1)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of human ERG by cell based automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 519663BDBM519663(US11142525, Example 64)
Affinity DataIC50: 0.170nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 519645BDBM519645(US11142525, Example 46 | US11684616, Example 300)
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human gamma-secretase by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50654269BDBM50654269(CHEMBL6102709)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human ERG by cell based automated patch clamp methodMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50654268BDBM50654268(CHEMBL6108993)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human ERG by cell based automated patch clamp methodMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50654264BDBM50654264(CHEMBL6147154)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human ERG by cell based automated patch clamp methodMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50654270BDBM50654270(CHEMBL6144977)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human ERG by cell based automated patch clamp methodMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50654265BDBM50654265(CHEMBL6149797)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human ERG by cell based automated patch clamp methodMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50654262BDBM50654262(CHEMBL6150317)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of human ERG by cell based automated patch clamp methodMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50654263BDBM50654263(CHEMBL6091907)
Affinity DataIC50: 10nMAssay Description:Inhibition of human ERG by cell based automated patch clamp methodMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50654261BDBM50654261(CHEMBL6145551)
Affinity DataIC50: 14nMAssay Description:Inhibition of VEGFR (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetLymphocyte cytosolic protein 2(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 606098BDBM606098(US11684616, Example 1)
Affinity DataIC50: 17nMAssay Description:Inhibition of postacid activity of 20s proteasome beta-1 subunit in HEK293 cells using Z-nLPnLD-Glo as substrate incubated for 2 hrs prior to substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50654267BDBM50654267(CHEMBL6151141)
Affinity DataIC50: 22nMAssay Description:Inhibition of human ERG by cell based automated patch clamp methodMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetLymphocyte cytosolic protein 2(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 519653BDBM519653(US11142525, Example 55)
Affinity DataIC50: 34nMAssay Description:Inhibition of human voltage-gated Na channel 1.5 by cell based patch clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetLymphocyte cytosolic protein 2(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 606195BDBM606195(US11684616, Example 201)
Affinity DataIC50: 37nMAssay Description:Inhibition of chymotrypsin-like activity of Proteasome subunit beta 5 (unknown origin) assessed as inhibition of beta-amyloid production by cell-base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetLymphocyte cytosolic protein 2(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 606204BDBM606204(US11684616, Example 210 | 4-[(methyl- amino)methyl...)
Affinity DataIC50: 47nMAssay Description:Inhibition of human voltage-gated Na channel 1.2 by cell based patch clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetLymphocyte cytosolic protein 2(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 606199BDBM606199(US11684616, Example 205 | 2-{6-[(5R)-5- (fluoromet...)
Affinity DataIC50: 52nMAssay Description:Inhibition of postacid activity of 20s proteasome beta-1 subunit in HEK293 cells using Z-nLPnLD-Glo as substrate incubated for 2 hrs prior to substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetLymphocyte cytosolic protein 2(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 606122BDBM606122(US11684616, Example 24 | 4-[(1$#958;)-1- aminoethy...)
Affinity DataIC50: 53nMAssay Description:Inhibition of postacid activity of 20s proteasome beta-1 subunit in HEK293 cells using Z-nLPnLD-Glo as substrate incubated for 2 hrs prior to substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetLymphocyte cytosolic protein 2(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 606178BDBM606178(US11684616, Example 140 | 4-[(1R)-1- aminopropyl]-...)
Affinity DataIC50: 53nMAssay Description:Inhibition of postacid activity of 20s proteasome beta-1 subunit in HEK293 cells using Z-nLPnLD-Glo as substrate incubated for 2 hrs prior to substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetLymphocyte cytosolic protein 2(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 519601BDBM519601(US11142525, Example 17)
Affinity DataIC50: 70nMAssay Description:Inhibition of LRRK2 (unknown origin) autophosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetLymphocyte cytosolic protein 2(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 519663BDBM519663(US11142525, Example 64)
Affinity DataIC50: 81nMAssay Description:Inhibition of human voltage-gated Na channel 1.7 by cell based patch clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetLymphocyte cytosolic protein 2(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 519662BDBM519662(US11142525, Example 63)
Affinity DataIC50: 87nMAssay Description:Inhibition of LRRK2 (unknown origin) autophosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetLymphocyte cytosolic protein 2(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 519585BDBM519585(US11142525, Example 1)
Affinity DataIC50: 112nMAssay Description:Inhibition of LRRK2 (unknown origin) autophosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetLymphocyte cytosolic protein 2(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654269BDBM50654269(CHEMBL6102709)
Affinity DataIC50: 115nMAssay Description:Inhibition of LRRK2 (unknown origin) autophosphorylation by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetLymphocyte cytosolic protein 2(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 519645BDBM519645(US11142525, Example 46 | US11684616, Example 300)
Affinity DataIC50: 121nMAssay Description:Inhibition of LRRK2 (unknown origin) autophosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetLymphocyte cytosolic protein 2(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654265BDBM50654265(CHEMBL6149797)
Affinity DataIC50: 139nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50654266BDBM50654266(CHEMBL6144192)
Affinity DataIC50: 194nMAssay Description:Inhibition of human ERG by cell based automated patch clamp methodMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetLymphocyte cytosolic protein 2(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654264BDBM50654264(CHEMBL6147154)
Affinity DataIC50: 222nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetLymphocyte cytosolic protein 2(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654268BDBM50654268(CHEMBL6108993)
Affinity DataIC50: 383nMAssay Description:Inhibition of LRRK2 (unknown origin) autophosphorylation by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetLymphocyte cytosolic protein 2(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654270BDBM50654270(CHEMBL6144977)
Affinity DataIC50: 520nMAssay Description:Inhibition of LRRK2 (unknown origin) autophosphorylation by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetLymphocyte cytosolic protein 2(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654263BDBM50654263(CHEMBL6091907)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetLymphocyte cytosolic protein 2(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654262BDBM50654262(CHEMBL6150317)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed