Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50022790
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654335BDBM50654335(CHEMBL6152502)
Affinity DataIC50: 0.670nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654353BDBM50654353(CHEMBL6133549)
Affinity DataIC50: 0.730nMAssay Description:Inhibition of rat recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654343BDBM50654343(CHEMBL6102991)
Affinity DataIC50: 0.860nMAssay Description:Inhibition of mouse endothelial lipase using PLAi as substrate measured for 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654345BDBM50654345(CHEMBL6146198)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of rat recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654333BDBM50654333(CHEMBL6101877)
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654334BDBM50654334(CHEMBL6159739)
Affinity DataIC50: 2.30nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654344BDBM50654344(CHEMBL6133598)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human endothelial lipase using PLAi as substrate measured for 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654352BDBM50654352(CHEMBL6144932)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654336BDBM50654336(CHEMBL6114901)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654356BDBM50654356(CHEMBL6143569)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of rat recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654346BDBM50654346(CHEMBL6101953)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of rat recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654357BDBM50654357(CHEMBL6144611)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of human recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654329BDBM50654329(CHEMBL6143822)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654358BDBM50654358(CHEMBL6134020)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654332BDBM50654332(CHEMBL6145438)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654330BDBM50654330(CHEMBL6133039)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654347BDBM50654347(CHEMBL6146160)
Affinity DataIC50: 17nMAssay Description:Inhibition of rat recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654337BDBM50654337(CHEMBL6091997)
Affinity DataIC50: 19nMAssay Description:Inhibition of mouse endothelial lipase using PLAi as substrate measured for 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654341BDBM50654341(CHEMBL6152461)
Affinity DataIC50: 19nMAssay Description:Inhibition of mouse endothelial lipase using PLAi as substrate measured for 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654355BDBM50654355(CHEMBL6141673)
Affinity DataIC50: 20nMAssay Description:Inhibition of rat recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654350BDBM50654350(CHEMBL6134732)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654349BDBM50654349(CHEMBL6134667)
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654354BDBM50654354(CHEMBL6162101)
Affinity DataIC50: 39nMAssay Description:Inhibition of rat recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654342BDBM50654342(CHEMBL6102817)
Affinity DataIC50: 41nMAssay Description:Inhibition of human endothelial lipase using PLAi as substrate measured for 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654351BDBM50654351(CHEMBL6101851)
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50327809BDBM50327809(1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluorometho...)
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654338BDBM50654338(CHEMBL6096608)
Affinity DataIC50: 54nMAssay Description:Inhibition of human endothelial lipase using PLAi as substrate measured for 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654331BDBM50654331(CHEMBL6143785)
Affinity DataIC50: 97nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654340BDBM50654340(CHEMBL6152896)
Affinity DataIC50: 143nMAssay Description:Inhibition of human endothelial lipase using PLAi as substrate measured for 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654348BDBM50654348(CHEMBL6144659)
Affinity DataIC50: 210nMAssay Description:Inhibition of rat recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Beijing Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654339BDBM50654339(CHEMBL6102919)
Affinity DataIC50: 2.65E+3nMAssay Description:Inhibition of mouse endothelial lipase using PLAi as substrate measured for 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed