Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50023549
TargetRAC-alpha serine/threonine-protein kinase(Human)
Toronto Metropolitan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 431867BDBM431867(US10550114, Compound 1a)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Toronto Metropolitan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313650BDBM50313650(8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]tr...)
Affinity DataIC50: 7nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Toronto Metropolitan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 15169BDBM15169(1-{1-[(4-{7-phenyl-1H-imidazo[4,5-g]quinoxalin-6-y...)
Affinity DataIC50: 58nMAssay Description:Inhibition of N-terminal hexa-histidine tagged AKT1 (1 to 443 residues) (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Toronto Metropolitan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50459706BDBM50459706(CHEMBL4214264)
Affinity DataIC50: 120nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSecernin-3(Homo sapiens)
Toronto Metropolitan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664987BDBM50664987(CHEMBL6172043)
Affinity DataIC50: 200nMAssay Description:Inhibition of full length human SCRN3 transfected in HEK293T cellsMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetNeutrophil elastase(Human)
Toronto Metropolitan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50610524BDBM50610524(CHEMBL5274237)
Affinity DataIC50: 240nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed