Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50022725
TargetOxysterols receptor LXR-alpha(Human)
Universite degli Studi di Perugia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653607BDBM50653607(CHEMBL6133610)
Affinity DataIC50: 150nMAssay Description:Antagonist activity against L-type calcium channel subunit alpha-1C assessed as inactivation of channel current by cell based patch clamp assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetOxysterols receptor LXR-alpha(Human)
Universite degli Studi di Perugia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653608BDBM50653608(CHEMBL6144761)
Affinity DataIC50: 310nMAssay Description:Antagonist activity against T-type calcium channel subunit alpha-1H assessed as inactivation of channel current by cell based patch clamp assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetOxysterols receptor LXR-beta(Human)
Universite degli Studi di Perugia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653603BDBM50653603(CHEMBL6078470)
Affinity DataIC50: 670nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by transient transfection cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetOxysterols receptor LXR-alpha(Human)
Universite degli Studi di Perugia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653603BDBM50653603(CHEMBL6078470)
Affinity DataIC50: 920nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by transient transfection cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetOxysterols receptor LXR-beta(Human)
Universite degli Studi di Perugia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653602BDBM50653602(CHEMBL6101888)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by transient transfection cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetOxysterols receptor LXR-alpha(Human)
Universite degli Studi di Perugia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653610BDBM50653610(CHEMBL6133811)
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [3H]-cDPPO from human Ephx2 by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetOxysterols receptor LXR-alpha(Human)
Universite degli Studi di Perugia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653602BDBM50653602(CHEMBL6101888)
Affinity DataIC50: 2.04E+3nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by transient transfection cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetOxysterols receptor LXR-beta(Human)
Universite degli Studi di Perugia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653604BDBM50653604(CHEMBL6083138)
Affinity DataIC50: 3.97E+3nMAssay Description:Inhibition of PDGFRbeta autophosphorylation by cell based Western blot analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetOxysterols receptor LXR-alpha(Human)
Universite degli Studi di Perugia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653604BDBM50653604(CHEMBL6083138)
Affinity DataIC50: 4.64E+3nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by transient transfection cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetOxysterols receptor LXR-alpha(Human)
Universite degli Studi di Perugia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653611BDBM50653611(CHEMBL4595729)
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of [3H]-cDPPO from human Ephx2 by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetOxysterols receptor LXR-alpha(Human)
Universite degli Studi di Perugia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653601BDBM50653601(CHEMBL6091981)
Affinity DataIC50: 5.18E+3nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by transient transfection cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetOxysterols receptor LXR-alpha(Human)
Universite degli Studi di Perugia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653606BDBM50653606(CHEMBL6078009)
Affinity DataIC50: 8.63E+3nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by transient transfection cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetOxysterols receptor LXR-beta(Human)
Universite degli Studi di Perugia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653605BDBM50653605(CHEMBL6102841)
Affinity DataIC50: 9.38E+3nMAssay Description:Inhibition of PDGFRbeta autophosphorylation by cell based Western blot analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetOxysterols receptor LXR-beta(Human)
Universite degli Studi di Perugia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653606BDBM50653606(CHEMBL6078009)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of rat Delta(5) fatty acid desaturase by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetOxysterols receptor LXR-alpha(Human)
Universite degli Studi di Perugia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653609BDBM50653609(Larsucosterol | Dur 928 | Dur-928 | 25HC3S | DUR-9...)
Affinity DataIC50: 1.26E+4nMAssay Description:Displacement of [3H]-cDPPO from human Ephx2 by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetOxysterols receptor LXR-alpha(Human)
Universite degli Studi di Perugia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653605BDBM50653605(CHEMBL6102841)
Affinity DataIC50: 1.46E+4nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by transient transfection cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetOxysterols receptor LXR-beta(Human)
Universite degli Studi di Perugia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653601BDBM50653601(CHEMBL6091981)
Affinity DataIC50: 8.25E+4nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by transient transfection cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed