Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50022926
TargetBile acid receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656294BDBM50656294(CHEMBL6133358)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetBile acid receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656295BDBM50656295(CHEMBL6145182)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAutotaxin(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50567227BDBM50567227(CHEMBL4858390)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of ATX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAutotaxin(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656297BDBM50656297(CHEMBL4117054)
Affinity DataIC50: 2nMAssay Description:Inhibition of ATX (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDiacylglycerol O-acyltransferase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003815BDBM50003815(CHEMBL3235321)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of DGAT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAutotaxin(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618715BDBM50618715(CHEMBL5439867)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of ATX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAutotaxin(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605359BDBM50605359(CHEMBL5177541)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of ATX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAutotaxin(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656296BDBM50656296(CHEMBL6151441)
Affinity DataIC50: 4nMAssay Description:Inhibition of ATX (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAutotaxin(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332927BDBM50332927(4-tetradecanamidobenzylphosphonic acid | CHEMBL163...)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of ATX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332927BDBM50332927(4-tetradecanamidobenzylphosphonic acid | CHEMBL163...)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of DGAT2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAutotaxin(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 446366BDBM446366((3aR,6aR)-5-(1H-benzotriazole-5-carbonyl)-hexahydr...)
Affinity DataIC50: 6nMAssay Description:Inhibition of ATX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 446366BDBM446366((3aR,6aR)-5-(1H-benzotriazole-5-carbonyl)-hexahydr...)
Affinity DataIC50: 6nMAssay Description:Inhibition of DGAT2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetBile acid receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656293BDBM50656293(CHEMBL6160526)
Affinity DataEC50:  13nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetBile acid receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50609062BDBM50609062(CHEMBL5271104)
Affinity DataEC50:  17nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAutotaxin(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50233165BDBM50233165(CHEMBL1222042)
Affinity DataIC50: 20nMAssay Description:Inhibition of ATX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656291BDBM50656291(CHEMBL6162275)
Affinity DataIC50: 24nMAssay Description:Inhibition of DGAT1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502586BDBM50502586(LCQ-908-NXA | LCQ-908NXA | LCQ908-NXA | Pradigasta...)
Affinity DataIC50: 55nMAssay Description:Inhibition of DGAT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetBile acid receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21724BDBM21724(3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...)
Affinity DataEC50:  59nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656290BDBM50656290(CHEMBL6120335)
Affinity DataIC50: 66nMAssay Description:Inhibition of DGAT1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656291BDBM50656291(CHEMBL6162275)
Affinity DataIC50: 76nMAssay Description:Inhibition of DGAT2 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656290BDBM50656290(CHEMBL6120335)
Affinity DataIC50: 76nMAssay Description:Inhibition of DGAT2 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656292BDBM50656292(Obeticholic acid | Acide obeticholique | Acido obe...)
Affinity DataIC50: 99nMAssay Description:Inhibition of DGAT2 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetBile acid receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50167161BDBM50167161((E)-3-{3-[Cyclohexanecarbonyl-(4'-dimethylamino-bi...)
Affinity DataEC50:  800nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAutotaxin(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 53721BDBM53721(MLS000028461 | Urso 250 | ursodeoxycholicacid | (4...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of ATX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPlatelet glycoprotein 4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656289BDBM50656289(CHEMBL6161924)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of N-terminal Flag-tagged human CD36More data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetCarnitine O-palmitoyltransferase 2, mitochondrial(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036210BDBM50036210((2S,3S)-3-Carboxy-2,3-dihydroxy-pentanedioic acid ...)
Affinity DataKi:  8.00E+3nMAssay Description:Binding affinity to CPT2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAutotaxin(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236230BDBM50236230(ursodeoxy cholic acid | 2-((R)-4-((3R,5S,7S,8R,9S,...)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of ATX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarnitine O-palmitoyltransferase 2, mitochondrial(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50018569BDBM50018569(CHEMBL63829 | 3,3,14,14-Tetramethyl-hexadecanedioi...)
Affinity DataKi:  1.60E+4nMAssay Description:Binding affinity to CPT2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed