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Found
30
Enz. Inhib. hit(s) with all data for entry = 50022930
Target
DNA (cytosine-5)-methyltransferase 1
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50656330
(CHEMBL6163134)
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Affinity Data
IC50: 1.80nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
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Target
Histone-lysine N-methyltransferase EHMT2
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM172038
(US10647700, Compound EPZ6438 | BDBM190183 | US1015...)
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Affinity Data
IC50: 2.90nM
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In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
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Target
Histone-lysine N-methyltransferase EHMT2
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50446376
(CHEMBL3109630)
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Affinity Data
IC50: 3.30nM
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In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
PDB
3D Structure (crystal)
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Target
Histone-lysine N-methyltransferase EHMT2
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50281297
(CHEMBL4170114)
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Affinity Data
IC50: 8nM
More data for this Ligand-Target Pair
Target Info
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PC cid
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In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
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Target
Histone-lysine N-methyltransferase EHMT1
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50300032
(6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-morphol...)
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Affinity Data
IC50: 13nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
PDB
3D Structure (crystal)
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Target
Histone-lysine N-methyltransferase EHMT2
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50300032
(6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-morphol...)
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Affinity Data
IC50: 13nM
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
PDB
3D Structure (crystal)
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Target
Histone-lysine N-methyltransferase EHMT2
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50300028
(N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-meth...)
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Affinity Data
Ki: 16nM
More data for this Ligand-Target Pair
Target Info
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PC sid
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In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
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Target
DNA (cytosine-5)-methyltransferase 1
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50613160
(CHEMBL5279012)
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Affinity Data
IC50: 27nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
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Target
Histone-lysine N-methyltransferase EHMT2
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50608123
(CHEMBL5281928)
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Affinity Data
IC50: 67nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
6/4/2026
Entry Details
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Target
Histone-lysine N-methyltransferase EHMT1/EHMT2
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50498655
(CHEMBL1895209)
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Affinity Data
IC50: 100nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
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Target
Histone-lysine N-methyltransferase EHMT2
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50656329
(CHEMBL6161933)
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Affinity Data
IC50: 126nM
More data for this Ligand-Target Pair
Target Info
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Date in BDB:
6/4/2026
Entry Details
PubMed
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Target
DNA (cytosine-5)-methyltransferase 1
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50281297
(CHEMBL4170114)
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Affinity Data
IC50: 382nM
More data for this Ligand-Target Pair
Target Info
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Ligand Info
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PC cid
PC sid
Similars
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
Copy reaction URL
Target
Histone-lysine N-methyltransferase EHMT1
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50300028
(N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-meth...)
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Affinity Data
IC50: 700nM
More data for this Ligand-Target Pair
Target Info
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GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
PDB
3D Structure (crystal)
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Target
Histone-lysine N-methyltransferase EHMT2
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50300028
(N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-meth...)
Copy SMILES
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Affinity Data
IC50: 1.90E+3nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
PC cid
PC sid
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In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
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Target
Histone-lysine N-methyltransferase EHMT2
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50442103
(CHEMBL2441082)
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Affinity Data
IC50: 2.50E+3nM
More data for this Ligand-Target Pair
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CHEMBL
PC cid
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In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
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Target
DNA (cytosine-5)-methyltransferase 1
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50656331
(CHEMBL120235)
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Affinity Data
IC50: 3.06E+3nM
More data for this Ligand-Target Pair
Target Info
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Date in BDB:
6/4/2026
Entry Details
PubMed
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Target
DNA (cytosine-5)-methyltransferase 1
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50526221
(CHEMBL4454542)
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Affinity Data
IC50: 3.10E+3nM
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PC sid
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In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
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Target
Histone-lysine N-methyltransferase EHMT2
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50353132
(CHEMBL1829305)
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Affinity Data
IC50: 4.00E+3nM
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Date in BDB:
6/4/2026
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Target
Histone-lysine N-methyltransferase EHMT2
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50346553
(CHEMBL1797937)
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Affinity Data
IC50: 4.70E+3nM
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Date in BDB:
6/4/2026
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Target
Protein arginine N-methyltransferase 1
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50346553
(CHEMBL1797937)
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Affinity Data
IC50: 6.00E+3nM
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CHEMBL
PC cid
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In Depth
Date in BDB:
6/4/2026
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PubMed
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Target
Histone-lysine N-methyltransferase EHMT2
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50353131
(CHEMBL1829304)
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Affinity Data
IC50: 6.00E+3nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
PC cid
PC sid
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In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
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Target
Histone-lysine N-methyltransferase EHMT2
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50075052
(CHEMBL3414617)
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Affinity Data
IC50: 6.30E+3nM
More data for this Ligand-Target Pair
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CHEMBL
PC cid
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In Depth
Date in BDB:
6/4/2026
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PubMed
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Target
DNA (cytosine-5)-methyltransferase 1
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50202440
(CHEMBL3933828)
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Affinity Data
IC50: 6.50E+3nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
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PC sid
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In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
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Target
Histone-lysine N-methyltransferase EHMT1/EHMT2
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50569835
(CHEMBL4850917)
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Affinity Data
IC50: 7.14E+3nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
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Target
Histone-lysine N-methyltransferase EHMT2
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50315537
(chaetocin | CHEMBL1089316)
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Affinity Data
IC50: 7.20E+3nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
6/4/2026
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Target
Histone-lysine N-methyltransferase EHMT2
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50656328
(CHEMBL6171235)
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Affinity Data
IC50: 1.20E+4nM
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Date in BDB:
6/4/2026
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Target
Histone deacetylase
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50569835
(CHEMBL4850917)
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Affinity Data
IC50: 1.38E+4nM
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In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
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Target
DNA (cytosine-5)-methyltransferase 1
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50030260
(CHEMBL3343657)
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Affinity Data
IC50: 1.63E+4nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
6/4/2026
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PubMed
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Target
Histone-lysine N-methyltransferase EZH2
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50498655
(CHEMBL1895209)
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Affinity Data
IC50: 2.40E+4nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
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Target
Histone-lysine N-methyltransferase EHMT2
(Human)
Sichuan University
Curated by
ChEMBL
Ligand
BDBM50378739
(SINEFUNGIN | jm2c00120, Sinefungin)
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IC50: 5.09E+5nM
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PC cid
PC sid
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In Depth
Date in BDB:
6/4/2026
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