Compile Data Set for Download or QSAR
Report error Found 54 Enz. Inhib. hit(s) with all data for entry = 50023107
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659218BDBM50659218(CHEMBL6163352)
Affinity DataIC50: 200nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659210BDBM50659210(CHEMBL6165723)
Affinity DataIC50: 300nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659217BDBM50659217(CHEMBL6168876)
Affinity DataIC50: 400nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659228BDBM50659228(CHEMBL6162618)
Affinity DataIC50: 600nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659220BDBM50659220(CHEMBL6151731)
Affinity DataIC50: 700nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659222BDBM50659222(CHEMBL6147664)
Affinity DataIC50: 800nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659211BDBM50659211(CHEMBL6143243)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659212BDBM50659212(CHEMBL6162300)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659223BDBM50659223(CHEMBL6163199)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659227BDBM50659227(CHEMBL6170447)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659225BDBM50659225(CHEMBL6163101)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659231BDBM50659231(CHEMBL6148412)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659213BDBM50659213(CHEMBL6149785)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659224BDBM50659224(CHEMBL6148530)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659229BDBM50659229(CHEMBL6143926)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659219BDBM50659219(CHEMBL6150580)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659216BDBM50659216(CHEMBL6170312)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 572839BDBM572839(US11453663, Preparative Example 157 | 2-cyano-3-(3...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 572707BDBM572707(US11453663, Preparative Example 141 | 2-(3,4-dihyd...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659204BDBM50659204(CHEMBL6120904)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659215BDBM50659215(CHEMBL6170744)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 572528BDBM572528(US11453663, Preparative Example 130 | 2-cyano-3-(3...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659221BDBM50659221(CHEMBL6143835)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659214BDBM50659214(CHEMBL6167522)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659226BDBM50659226(CHEMBL6162856)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659209BDBM50659209(CHEMBL6165271)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659231BDBM50659231(CHEMBL6148412)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659204BDBM50659204(CHEMBL6120904)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of MRE11 in human U2OS cells assessed as inhibition of pS4/S8 RPA 32 level incubated for 1 hr followed by treatment with camptothecin for ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetFlap endonuclease 1(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659231BDBM50659231(CHEMBL6148412)
Affinity DataIC50: 2.42E+4nMAssay Description:Inhibition of human FEN1 expressed in Escherichia coli cells using 5'-Flap DNA as substrate preincubated for 20 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659208BDBM50659208(CHEMBL6145598)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659204BDBM50659204(CHEMBL6120904)
Affinity DataIC50: 2.53E+4nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659231BDBM50659231(CHEMBL6148412)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of MRE11 in human U2OS cells assessed as inhibition of pS4/S8 RPA 32 level incubated for 1 hr followed by treatment with camptothecin for ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659233BDBM50659233(CHEMBL6152547)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659232BDBM50659232(CHEMBL6165586)
Affinity DataIC50: 3.65E+4nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659232BDBM50659232(CHEMBL6165586)
Affinity DataIC50: 3.69E+4nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659204BDBM50659204(CHEMBL6120904)
Affinity DataIC50: 3.80E+4nMAssay Description:Binding affinity to MRE11 in human U2OS cells assessed as destabilization of protein incubated for 60 mins followed by exposure to temperature of 49 ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659233BDBM50659233(CHEMBL6152547)
Affinity DataIC50: 4.31E+4nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659230BDBM50659230(CHEMBL6144317)
Affinity DataIC50: 4.65E+4nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659205BDBM50659205(CHEMBL6144767)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659207BDBM50659207(CHEMBL6170235)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659206BDBM50659206(CHEMBL6152979)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetFlap endonuclease 1(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659204BDBM50659204(CHEMBL6120904)
Affinity DataIC50: 8.27E+4nMAssay Description:Inhibition of human FEN1 expressed in Escherichia coli cells using 5'-Flap DNA as substrate preincubated for 20 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659235BDBM50659235(MIRIN)
Affinity DataIC50: 1.15E+5nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659234BDBM50659234(CHEMBL4527793)
Affinity DataIC50: 1.17E+5nMAssay Description:Inhibition of human MRE11 expressed in insect High Five cells using fluorescent-labeled 5'-overhang DNA as substrate preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetFlap endonuclease 1(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659232BDBM50659232(CHEMBL6165586)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human FEN1 expressed in Escherichia coli cells using 5'-Flap DNA as substrate preincubated for 20 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDouble-strand break repair protein MRE11(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659235BDBM50659235(MIRIN)
Affinity DataIC50: 1.38E+5nMAssay Description:Inhibition of MRE11 in human U2OS cells assessed as inhibition of pS4/S8 RPA 32 level incubated for 1 hr followed by treatment with camptothecin for ...More data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetExonuclease 1(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659231BDBM50659231(CHEMBL6148412)
Affinity DataIC50: 1.76E+5nMAssay Description:Inhibition of human EXO1 expressed in Escherichia coli BL21 (RIPL) cells using 3'-overhang DNA as substrate preincubated for 20 mins followed by subs...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetFlap endonuclease 1(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659234BDBM50659234(CHEMBL4527793)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human FEN1 expressed in Escherichia coli cells using 5'-Flap DNA as substrate preincubated for 20 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetFlap endonuclease 1(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659233BDBM50659233(CHEMBL6152547)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human FEN1 expressed in Escherichia coli cells using 5'-Flap DNA as substrate preincubated for 20 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetExonuclease 1(Human)
Masaryk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659233BDBM50659233(CHEMBL6152547)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human EXO1 expressed in Escherichia coli BL21 (RIPL) cells using 3'-overhang DNA as substrate preincubated for 20 mins followed by subs...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
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