Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50023652
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666326BDBM50666326(CHEMBL6176298)
Affinity DataKd:  430nMAssay Description:Binding affinity to wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666326BDBM50666326(CHEMBL6176298)
Affinity DataKd:  570nMAssay Description:Competitive inhibition of wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 using hmdUMP as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016805BDBM50016805(CHEMBL3274191)
Affinity DataKd:  600nMAssay Description:Competitive inhibition of wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 using hmdUMP as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666328BDBM50666328(CHEMBL6177387)
Affinity DataKi:  610nMAssay Description:Competitive inhibition of wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 using hmdUMP as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016805BDBM50016805(CHEMBL3274191)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 assessed as decrease in hmdUMP hydrolysis preincubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666340BDBM50666340(CHEMBL6176738)
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity to wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666326BDBM50666326(CHEMBL6176298)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 assessed as decrease in hmdUMP hydrolysis preincubated for 30 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666329BDBM50666329(CHEMBL6175626)
Affinity DataKi:  2.85E+3nMAssay Description:Competitive inhibition of wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 using hmdUMP as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666340BDBM50666340(CHEMBL6176738)
Affinity DataKi:  3.30E+3nMAssay Description:Competitive inhibition of wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 using hmdUMP as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666330BDBM50666330(CHEMBL6172195)
Affinity DataKi:  3.67E+3nMAssay Description:Competitive inhibition of wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 using hmdUMP as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666332BDBM50666332(CHEMBL6162899)
Affinity DataKi:  5.14E+3nMAssay Description:Competitive inhibition of wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 using hmdUMP as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666331BDBM50666331(CHEMBL6168678)
Affinity DataKi:  5.17E+3nMAssay Description:Competitive inhibition of wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 using hmdUMP as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666344BDBM50666344(CHEMBL6176336)
Affinity DataKd:  6.30E+3nMAssay Description:Binding affinity to DNPH1 (unknown origin) assessed as equilibrium constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666333BDBM50666333(CHEMBL6176941)
Affinity DataKi:  6.50E+3nMAssay Description:Competitive inhibition of wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 using hmdUMP as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666334BDBM50666334(CHEMBL6174422)
Affinity DataKi:  1.23E+4nMAssay Description:Competitive inhibition of wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 using hmdUMP as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010318BDBM50010318(CHEMBL283807 | CHEBI:17345)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibition of DNPH1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666335BDBM50666335(CHEMBL6167192)
Affinity DataKi:  2.07E+4nMAssay Description:Competitive inhibition of wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 using hmdUMP as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666336BDBM50666336(CHEMBL6176243)
Affinity DataKi:  2.58E+4nMAssay Description:Competitive inhibition of wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 using hmdUMP as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666337BDBM50666337(CHEMBL6177042)
Affinity DataKi:  3.68E+4nMAssay Description:Competitive inhibition of wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 using hmdUMP as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18137BDBM18137(adenosine 5 -monophosphate | CHEMBL752 | [(2R,3S,4...)
Affinity DataKi:  4.10E+4nMAssay Description:Inhibition of DNPH1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666341BDBM50666341(CHEMBL6176951)
Affinity DataKi: >5.00E+4nMAssay Description:Competitive inhibition of wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 using hmdUMP as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666342BDBM50666342(CHEMBL1236914)
Affinity DataKi: >5.00E+4nMAssay Description:Competitive inhibition of wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 using hmdUMP as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666327BDBM50666327(CHEMBL6175937)
Affinity DataKd: >5.00E+4nMAssay Description:Competitive inhibition of wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 using hmdUMP as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666343BDBM50666343(CHEMBL6177776)
Affinity DataKi: >5.00E+4nMAssay Description:Competitive inhibition of wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 using hmdUMP as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666338BDBM50666338(CHEMBL6176526)
Affinity DataKi: >5.00E+4nMAssay Description:Competitive inhibition of wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 using hmdUMP as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666339BDBM50666339(CHEMBL6177402)
Affinity DataKi: >5.00E+4nMAssay Description:Competitive inhibition of wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 using hmdUMP as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666327BDBM50666327(CHEMBL6175937)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 assessed as decrease in hmdUMP hydrolysis preincubated for 30 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed