Compile Data Set for Download or QSAR
Report error Found 142 Enz. Inhib. hit(s) with all data for entry = 50023200
TargetATP-dependent translocase ABCB1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660330BDBM50660330(CHEMBL6163420)
Affinity DataEC50:  89nMAssay Description:Reversal of ABCB1-mediated multidrug resistance in human A2780 ADR cells assessed as increase in doxorubicin-mediated cytotoxicity incubated for 72 h...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 2B1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660333BDBM50660333(CHEMBL6162249)
Affinity DataIC50: 124nMAssay Description:Inhibition of OATP2B1 (unknown origin) transfected in human A-431 cells assessed as inhibition of pyranine uptake preincubated for 5 mins followed by...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 2B1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660331BDBM50660331(CHEMBL6171119)
Affinity DataIC50: 155nMAssay Description:Inhibition of OATP2B1 (unknown origin) transfected in human A-431 cells assessed as inhibition of pyranine uptake preincubated for 5 mins followed by...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 2B1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660330BDBM50660330(CHEMBL6163420)
Affinity DataIC50: 167nMAssay Description:Inhibition of OATP2B1 (unknown origin) transfected in human A-431 cells assessed as inhibition of pyranine uptake preincubated for 5 mins followed by...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 2B1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660326BDBM50660326(CHEMBL6150561)
Affinity DataIC50: 170nMAssay Description:Inhibition of OATP2B1 (unknown origin) transfected in human A-431 cells assessed as inhibition of pyranine uptake preincubated for 5 mins followed by...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 1A2(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660333BDBM50660333(CHEMBL6162249)
Affinity DataIC50: 237nMAssay Description:Inhibition of OATP1A2 (unknown origin) transfected in human A-431 cells assessed as inhibition of SR101 uptake preincubated for 5 mins followed by SR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 2B1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660328BDBM50660328(CHEMBL6151074)
Affinity DataIC50: 265nMAssay Description:Inhibition of OATP2B1 (unknown origin) transfected in human A-431 cells assessed as inhibition of pyranine uptake preincubated for 5 mins followed by...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660330BDBM50660330(CHEMBL6163420)
Affinity DataEC50:  326nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance transfected in dog MDCK-II-BCRP cells assessed as increase in SN-38-mediated cytotox...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 2B1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660327BDBM50660327(CHEMBL6172851)
Affinity DataIC50: 387nMAssay Description:Inhibition of OATP2B1 (unknown origin) transfected in human A-431 cells assessed as inhibition of pyranine uptake preincubated for 5 mins followed by...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 2B1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660329BDBM50660329(CHEMBL6161092)
Affinity DataIC50: 402nMAssay Description:Inhibition of OATP2B1 (unknown origin) transfected in human A-431 cells assessed as inhibition of pyranine uptake preincubated for 5 mins followed by...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 2B1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660325BDBM50660325(CHEMBL6161464)
Affinity DataIC50: 420nMAssay Description:Inhibition of OATP2B1 (unknown origin) transfected in human A-431 cells assessed as inhibition of pyranine uptake preincubated for 5 mins followed by...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 1A2(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660334BDBM50660334(CHEMBL6146403)
Affinity DataIC50: 420nMAssay Description:Inhibition of OATP1A2 (unknown origin) transfected in human A-431 cells assessed as inhibition of SR101 uptake preincubated for 5 mins followed by SR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 1A2(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660331BDBM50660331(CHEMBL6171119)
Affinity DataIC50: 422nMAssay Description:Inhibition of OATP1A2 (unknown origin) transfected in human A-431 cells assessed as inhibition of SR101 uptake preincubated for 5 mins followed by SR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMultidrug resistance-associated protein 1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660330BDBM50660330(CHEMBL6163420)
Affinity DataIC50: 492nMAssay Description:Inhibition of ABCC1 in human NCI-H69AR cells assessed as increase in daunorubicin fluorescence intensity using daunorubicin as tracer preincubated fo...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660325BDBM50660325(CHEMBL6161464)
Affinity DataEC50:  504nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance transfected in dog MDCK-II-BCRP cells assessed as increase in SN-38-mediated cytotox...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 2B1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660334BDBM50660334(CHEMBL6146403)
Affinity DataIC50: 583nMAssay Description:Inhibition of OATP2B1 (unknown origin) transfected in human A-431 cells assessed as inhibition of pyranine uptake preincubated for 5 mins followed by...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660333BDBM50660333(CHEMBL6162249)
Affinity DataEC50:  603nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance transfected in dog MDCK-II-BCRP cells assessed as increase in SN-38-mediated cytotox...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660332BDBM50660332(CHEMBL6161472)
Affinity DataEC50:  604nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance transfected in dog MDCK-II-BCRP cells assessed as increase in SN-38-mediated cytotox...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660330BDBM50660330(CHEMBL6163420)
Affinity DataIC50: 626nMAssay Description:Inhibition of ABCB1 in human A2780 ADR cells assessed as increase in calcein-AM fluorescence intensity using calcein-AM as tracer preincubated for 30...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660332BDBM50660332(CHEMBL6161472)
Affinity DataIC50: 688nMAssay Description:Inhibition of ABCB1 in human A2780 ADR cells assessed as increase in calcein-AM fluorescence intensity using calcein-AM as tracer preincubated for 30...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 1A2(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660326BDBM50660326(CHEMBL6150561)
Affinity DataIC50: 710nMAssay Description:Inhibition of OATP1A2 (unknown origin) transfected in human A-431 cells assessed as inhibition of SR101 uptake preincubated for 5 mins followed by SR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 1B3(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660326BDBM50660326(CHEMBL6150561)
Affinity DataIC50: 788nMAssay Description:Inhibition of OATP1B3 (unknown origin) transfected in human A-431 cells assessed as inhibition of DHPDS uptake preincubated for 5 mins followed by DH...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 2B1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660332BDBM50660332(CHEMBL6161472)
Affinity DataIC50: 826nMAssay Description:Inhibition of OATP2B1 (unknown origin) transfected in human A-431 cells assessed as inhibition of pyranine uptake preincubated for 5 mins followed by...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660327BDBM50660327(CHEMBL6172851)
Affinity DataEC50:  939nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance transfected in dog MDCK-II-BCRP cells assessed as increase in SN-38-mediated cytotox...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 1A2(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660327BDBM50660327(CHEMBL6172851)
Affinity DataIC50: 991nMAssay Description:Inhibition of OATP1A2 (unknown origin) transfected in human A-431 cells assessed as inhibition of SR101 uptake preincubated for 5 mins followed by SR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 1A2(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660328BDBM50660328(CHEMBL6151074)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of OATP1A2 (unknown origin) transfected in human A-431 cells assessed as inhibition of SR101 uptake preincubated for 5 mins followed by SR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660330BDBM50660330(CHEMBL6163420)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in dog MDCK-II-BCRP cells assessed as increase in Hoechst 33342 fluorescence intensity using Hoechst 3...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660331BDBM50660331(CHEMBL6171119)
Affinity DataEC50:  1.05E+3nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance transfected in dog MDCK-II-BCRP cells assessed as increase in SN-38-mediated cytotox...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660332BDBM50660332(CHEMBL6161472)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of ABCB1 in human A2780 ADR cells assessed as increase in daunorubicin fluorescence intensity using daunorubicin as tracer preincubated fo...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660334BDBM50660334(CHEMBL6146403)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of ABCB1 in human A2780 ADR cells assessed as increase in calcein-AM fluorescence intensity using calcein-AM as tracer preincubated for 30...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660328BDBM50660328(CHEMBL6151074)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of ABCB1 in human A2780 ADR cells assessed as increase in calcein-AM fluorescence intensity using calcein-AM as tracer preincubated for 30...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660330BDBM50660330(CHEMBL6163420)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in dog MDCK-II-BCRP cells assessed as increase in pheophorbide A fluorescence intensity using pheophor...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 1A2(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660325BDBM50660325(CHEMBL6161464)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of OATP1A2 (unknown origin) transfected in human A-431 cells assessed as inhibition of SR101 uptake preincubated for 5 mins followed by SR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 1A2(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660330BDBM50660330(CHEMBL6163420)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of OATP1A2 (unknown origin) transfected in human A-431 cells assessed as inhibition of SR101 uptake preincubated for 5 mins followed by SR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660334BDBM50660334(CHEMBL6146403)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in dog MDCK-II-BCRP cells assessed as increase in pheophorbide A fluorescence intensity using pheophor...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660332BDBM50660332(CHEMBL6161472)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in dog MDCK-II-BCRP cells assessed as increase in Hoechst 33342 fluorescence intensity using Hoechst 3...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660334BDBM50660334(CHEMBL6146403)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of ABCB1 in human A2780 ADR cells assessed as increase in daunorubicin fluorescence intensity using daunorubicin as tracer preincubated fo...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMultidrug resistance-associated protein 1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660334BDBM50660334(CHEMBL6146403)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of ABCC1 in human NCI-H69AR cells assessed as increase in daunorubicin fluorescence intensity using daunorubicin as tracer preincubated fo...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660333BDBM50660333(CHEMBL6162249)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of ABCB1 in human A2780 ADR cells assessed as increase in calcein-AM fluorescence intensity using calcein-AM as tracer preincubated for 30...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660325BDBM50660325(CHEMBL6161464)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of ABCB1 in human A2780 ADR cells assessed as increase in calcein-AM fluorescence intensity using calcein-AM as tracer preincubated for 30...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660333BDBM50660333(CHEMBL6162249)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in dog MDCK-II-BCRP cells assessed as increase in pheophorbide A fluorescence intensity using pheophor...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660330BDBM50660330(CHEMBL6163420)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of ABCB1 in human A2780 ADR cells assessed as increase in daunorubicin fluorescence intensity using daunorubicin as tracer preincubated fo...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 1B3(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660325BDBM50660325(CHEMBL6161464)
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of OATP1B3 (unknown origin) transfected in human A-431 cells assessed as inhibition of DHPDS uptake preincubated for 5 mins followed by DH...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 1B3(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660333BDBM50660333(CHEMBL6162249)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of OATP1B3 (unknown origin) transfected in human A-431 cells assessed as inhibition of DHPDS uptake preincubated for 5 mins followed by DH...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 1B3(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660331BDBM50660331(CHEMBL6171119)
Affinity DataIC50: 1.84E+3nMAssay Description:Inhibition of OATP1B3 (unknown origin) transfected in human A-431 cells assessed as inhibition of DHPDS uptake preincubated for 5 mins followed by DH...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660330BDBM50660330(CHEMBL6163420)
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of MCT-1 in human A549 cells assessed as potentiation of 3-BP-mediated cytotoxicity by measuring decrease in cell viability incubated for ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660326BDBM50660326(CHEMBL6150561)
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of ABCB1 in human A2780 ADR cells assessed as increase in calcein-AM fluorescence intensity using calcein-AM as tracer preincubated for 30...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660328BDBM50660328(CHEMBL6151074)
Affinity DataEC50:  1.95E+3nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance transfected in dog MDCK-II-BCRP cells assessed as increase in SN-38-mediated cytotox...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660334BDBM50660334(CHEMBL6146403)
Affinity DataEC50:  2.01E+3nMAssay Description:Reversal of ABCB1-mediated multidrug resistance in human A2780 ADR cells assessed as increase in doxorubicin-mediated cytotoxicity incubated for 72 h...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMultidrug resistance-associated protein 1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660325BDBM50660325(CHEMBL6161464)
Affinity DataIC50: 2.04E+3nMAssay Description:Inhibition of ABCC1 in human NCI-H69AR cells assessed as increase in rhodamine123 fluorescence intensity using rhodamine123 as tracer preincubated fo...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
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