Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50023434
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Icahn School of Medicine at Mount Sinai

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 491199BDBM491199(US10975056, Example 143)
Affinity DataIC50: 61nMAssay Description:Inhibition of human DNMT1 (350 to 1600 residues) extracted from Escherichia coli BL21 (DE3)-codon plus-RIL cells in presence of SAM and hemimethylate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Icahn School of Medicine at Mount Sinai

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663605BDBM50663605(CHEMBL6164609)
Affinity DataIC50: 430nMAssay Description:Inhibition of human DNMT1 (350 to 1600 residues) extracted from Escherichia coli BL21 (DE3)-codon plus-RIL cells in presence of SAM and hemimethylate...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Icahn School of Medicine at Mount Sinai

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663606BDBM50663606(CHEMBL6172792)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human DNMT1 (350 to 1600 residues) extracted from Escherichia coli BL21 (DE3)-codon plus-RIL cells in presence of SAM and hemimethylate...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed