Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50023122
TargetEpidermal growth factor receptor(Human)
Beni-Suef University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5446BDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human EGFR T790M mutant by Kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Beni-Suef University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029668BDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 37nMAssay Description:Inhibition of human EGFR T790M mutant by Kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Beni-Suef University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5446BDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 52nMAssay Description:Inhibition of human wild-type EGFR by Kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Beni-Suef University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029668BDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human wild-type EGFR by Kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Beni-Suef University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659383BDBM50659383(CHEMBL6133704)
Affinity DataIC50: 76nMAssay Description:Inhibition of human EGFR T790M mutant by Kinase-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Beni-Suef University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659383BDBM50659383(CHEMBL6133704)
Affinity DataIC50: 121nMAssay Description:Inhibition of human wild-type EGFR by Kinase-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Beni-Suef University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659384BDBM50659384(CHEMBL6164518)
Affinity DataIC50: 135nMAssay Description:Inhibition of human EGFR T790M mutant by Kinase-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Beni-Suef University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659384BDBM50659384(CHEMBL6164518)
Affinity DataIC50: 216nMAssay Description:Inhibition of human wild-type EGFR by Kinase-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Beni-Suef University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659382BDBM50659382(CHEMBL6161294)
Affinity DataIC50: 423nMAssay Description:Inhibition of human wild-type EGFR by Kinase-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Beni-Suef University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659384BDBM50659384(CHEMBL6164518)
Affinity DataIC50: 560nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Beni-Suef University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659382BDBM50659382(CHEMBL6161294)
Affinity DataIC50: 764nMAssay Description:Inhibition of human EGFR T790M mutant by Kinase-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Beni-Suef University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659383BDBM50659383(CHEMBL6133704)
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Beni-Suef University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11639BDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 3.33E+3nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Beni-Suef University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659382BDBM50659382(CHEMBL6161294)
Affinity DataIC50: 4.69E+3nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
Beni-Suef University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17638BDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 6.59E+3nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
Beni-Suef University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659384BDBM50659384(CHEMBL6164518)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Beni-Suef University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17638BDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 1.74E+4nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Human)
Beni-Suef University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659383BDBM50659383(CHEMBL6133704)
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
Beni-Suef University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11639BDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
Beni-Suef University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659382BDBM50659382(CHEMBL6161294)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed