Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50023681
TargetCystic fibrosis transmembrane conductance regulator(Human)
Istituto Italiano di Tecnologia (IIT)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666706BDBM50666706(CHEMBL6177416)
Affinity DataEC50: <3nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing HS-YFP assessed as restoration of channel ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Istituto Italiano di Tecnologia (IIT)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666705BDBM50666705(CHEMBL6173991)
Affinity DataEC50: <3nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing HS-YFP assessed as restoration of channel ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Istituto Italiano di Tecnologia (IIT)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666707BDBM50666707(CHEMBL6177322)
Affinity DataEC50:  3.30nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing HS-YFP assessed as restoration of channel ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Istituto Italiano di Tecnologia (IIT)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666704BDBM50666704(CHEMBL6177436)
Affinity DataEC50:  24nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing HS-YFP assessed as restoration of channel ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Istituto Italiano di Tecnologia (IIT)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666709BDBM50666709(CHEMBL6177294)
Affinity DataEC50:  122nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing HS-YFP assessed as restoration of channel ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Istituto Italiano di Tecnologia (IIT)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666708BDBM50666708(CHEMBL6162568)
Affinity DataEC50:  385nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing HS-YFP assessed as restoration of channel ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Istituto Italiano di Tecnologia (IIT)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666710BDBM50666710(CHEMBL6176900)
Affinity DataEC50:  480nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing HS-YFP assessed as restoration of channel ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed