Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50023308
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040805BDBM50040805(CHEMBL3361255)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to IRAK4 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5445BDBM5445(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(...)
Affinity DataIC50: 3nMAssay Description:Inhibition of N/C terminal GST/6xHis-tagged human recombinant EGFR (668 to 1210 residues) extracted from Sf9 cells using Poly (Glu, Tyr) as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 25028BDBM25028(4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpipera...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 25028BDBM25028(4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpipera...)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040806BDBM50040806(CHEMBL3361254)
Affinity DataKi:  7.5nMAssay Description:Binding affinity to IRAK4 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5445BDBM5445(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(...)
Affinity DataIC50: 15nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant HER-2 (679 to 1255 residues) extracted from Sf9 cells using poly (Glu:Tyr)(4:1) as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661672BDBM50661672(CHEMBL6150902)
Affinity DataIC50: 21nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant VEGFR-2 (805 to 1356 residues) extracted from Sf9 cells by kinase assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661670BDBM50661670(CHEMBL6172985)
Affinity DataIC50: 33nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant VEGFR-2 (805 to 1356 residues) extracted from Sf9 cells by kinase assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 25028BDBM25028(4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpipera...)
Affinity DataIC50: 33nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 25028BDBM25028(4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpipera...)
Affinity DataIC50: 46nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661671BDBM50661671(CHEMBL6144806)
Affinity DataIC50: 47nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant VEGFR-2 (805 to 1356 residues) extracted from Sf9 cells by kinase assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16673BDBM16673(BAY439006 | CHEMBL1336 | BAY 43-9006 | 4-[4-({[4-c...)
Affinity DataIC50: 90nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant VEGFR-2 (805 to 1356 residues) extracted from Sf9 cells by kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase mTOR(Human)
Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25028BDBM25028(4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpipera...)
Affinity DataIC50: 134nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetFas-activated serine/threonine kinase(Homo sapiens)
Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661668BDBM50661668(CHEMBL6165181)
Affinity DataIC50: 150nMAssay Description:Inhibition of full length human FASTK (355 to 444 residues) extracted from Escherichia coli BL21 (DE3) by Malachite Green dye based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetFas-activated serine/threonine kinase(Homo sapiens)
Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661667BDBM50661667(CHEMBL6168517)
Affinity DataIC50: 170nMAssay Description:Inhibition of full length human FASTK (355 to 444 residues) extracted from Escherichia coli BL21 (DE3) by Malachite Green dye based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetFas-activated serine/threonine kinase(Homo sapiens)
Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661666BDBM50661666(CHEMBL6159585)
Affinity DataIC50: 320nMAssay Description:Inhibition of full length human FASTK (355 to 444 residues) extracted from Escherichia coli BL21 (DE3) by Malachite Green dye based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661669BDBM50661669(CHEMBL6120509)
Affinity DataIC50: 454nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant VEGFR-2 (805 to 1356 residues) extracted from Sf9 cells by kinase assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed