Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50023790
TargetProstaglandin G/H synthase 2(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102311BDBM50102311(3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-6...)
Affinity DataIC50: 12nMAssay Description:Inhibition of COX-2 in human 143.98.2 cells preincubated for 15 mins followed by arachidonic acid addition and measured after 10 mins by by enzyme im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056998BDBM50056998(Meloxicam sodium | 4-Hydroxy-2-methyl-1,1-dioxo-1,...)
Affinity DataIC50: 35nMAssay Description:Inhibition of COX-1 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11639BDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 47nMAssay Description:Inhibition of COX-2 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611295BDBM50611295(CHEMBL5289655)
Affinity DataIC50: 47nMAssay Description:Inhibition of human COX-2 using acetylcholinesterase as substrate preincubated for 10 mins followed by substrate addition and measured after 30 sec b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056998BDBM50056998(Meloxicam sodium | 4-Hydroxy-2-methyl-1,1-dioxo-1,...)
Affinity DataIC50: 52nMAssay Description:Inhibition of COX-2 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668322BDBM50668322(CHEMBL6188587)
Affinity DataIC50: 53nMAssay Description:Inhibition of COX-2 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668325BDBM50668325(CHEMBL6189784)
Affinity DataIC50: 60nMAssay Description:Inhibition of COX-2 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668320BDBM50668320(CHEMBL6192955)
Affinity DataIC50: 60nMAssay Description:Inhibition of COX-2 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668318BDBM50668318(CHEMBL6190623)
Affinity DataIC50: 68nMAssay Description:Inhibition of COX-2 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668319BDBM50668319(CHEMBL6192453)
Affinity DataIC50: 73nMAssay Description:Inhibition of COX-2 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11639BDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 80nMAssay Description:Inhibition of COX-2 in human 143.98.2 cells preincubated for 15 mins followed by arachidonic acid addition and measured after 10 mins by by enzyme im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668326BDBM50668326(CHEMBL6192653)
Affinity DataIC50: 88nMAssay Description:Inhibition of COX-2 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11639BDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 95nMAssay Description:Inhibition of human COX-2 using acetylcholinesterase as substrate preincubated for 10 mins followed by substrate addition and measured after 30 sec b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668321BDBM50668321(CHEMBL6193598)
Affinity DataIC50: 96nMAssay Description:Inhibition of COX-2 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668323BDBM50668323(CHEMBL6191878)
Affinity DataIC50: 118nMAssay Description:Inhibition of COX-2 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11639BDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 123nMAssay Description:Inhibition of COX-1 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668325BDBM50668325(CHEMBL6189784)
Affinity DataIC50: 169nMAssay Description:Inhibition of COX-1 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11639BDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 188nMAssay Description:Inhibition of human COX-1 using acetylcholinesterase as substrate preincubated for 10 mins followed by substrate addition and measured after 30 sec b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668324BDBM50668324(CHEMBL6190014)
Affinity DataIC50: 255nMAssay Description:Inhibition of COX-2 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50610886BDBM50610886(CHEMBL5274509)
Affinity DataIC50: 284nMAssay Description:Inhibition of human COX-2 using acetylcholinesterase as substrate preincubated for 10 mins followed by substrate addition and measured after 30 sec b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668320BDBM50668320(CHEMBL6192955)
Affinity DataIC50: 476nMAssay Description:Inhibition of COX-1 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611293BDBM50611293(CHEMBL5278682)
Affinity DataIC50: 488nMAssay Description:Inhibition of human COX-2 using acetylcholinesterase as substrate preincubated for 10 mins followed by substrate addition and measured after 30 sec b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611293BDBM50611293(CHEMBL5278682)
Affinity DataIC50: 600nMAssay Description:Inhibition of 5-LOX (unknown origin) by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611295BDBM50611295(CHEMBL5289655)
Affinity DataIC50: 668nMAssay Description:Inhibition of human COX-1 using acetylcholinesterase as substrate preincubated for 10 mins followed by substrate addition and measured after 30 sec b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50610886BDBM50610886(CHEMBL5274509)
Affinity DataIC50: 684nMAssay Description:Inhibition of human COX-1 using acetylcholinesterase as substrate preincubated for 10 mins followed by substrate addition and measured after 30 sec b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668322BDBM50668322(CHEMBL6188587)
Affinity DataIC50: 758nMAssay Description:Inhibition of COX-1 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000541BDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 800nMAssay Description:Inhibition of 5-LOX (unknown origin) by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000541BDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 800nMAssay Description:Inhibition of 5-LOX (unknown origin) by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50610886BDBM50610886(CHEMBL5274509)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 5-LOX (unknown origin) by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611380BDBM50611380(CHEMBL5280862)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of ovine COX-2 by EIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11639BDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of ovine COX-2 by EIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611379BDBM50611379(CHEMBL5275045)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of ovine COX-2 by EIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611293BDBM50611293(CHEMBL5278682)
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of human COX-1 using acetylcholinesterase as substrate preincubated for 10 mins followed by substrate addition and measured after 30 sec b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668322BDBM50668322(CHEMBL6188587)
Affinity DataIC50: 2.29E+3nMAssay Description:Inhibition of 5-LOX (unknown origin) by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611295BDBM50611295(CHEMBL5289655)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of 5-LOX (unknown origin) by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668320BDBM50668320(CHEMBL6192955)
Affinity DataIC50: 4.57E+3nMAssay Description:Inhibition of 5-LOX (unknown origin) by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Al-Azhar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668325BDBM50668325(CHEMBL6189784)
Affinity DataIC50: 5.29E+3nMAssay Description:Inhibition of 5-LOX (unknown origin) by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed