Compile Data Set for Download or QSAR
Report error Found 74 Enz. Inhib. hit(s) with all data for entry = 50023228
TargetTGF-beta receptor type-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660651BDBM50660651(CHEMBL6167230)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660656BDBM50660656(CHEMBL6169687)
Affinity DataIC50: 2nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660652BDBM50660652(CHEMBL6161653)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660645BDBM50660645(CHEMBL6168217)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660650BDBM50660650(CHEMBL6169657)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645537BDBM50645537(CHEMBL5594704)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660649BDBM50660649(CHEMBL6165023)
Affinity DataIC50: 3nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50015639BDBM50015639(CHEMBL3260567 | USRE47141, Example 2)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660655BDBM50660655(CHEMBL6167281)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660663BDBM50660663(CHEMBL6172244)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660644BDBM50660644(CHEMBL6172073)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660653BDBM50660653(CHEMBL6166782)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660657BDBM50660657(CHEMBL6151974)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetActivin receptor type-1C(Homo sapiens)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660663BDBM50660663(CHEMBL6172244)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of ALK7 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAurora kinase C(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660656BDBM50660656(CHEMBL6169687)
Affinity DataIC50: 11nMAssay Description:Inhibition of Aurora Kinase C (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAurora kinase C(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660652BDBM50660652(CHEMBL6161653)
Affinity DataIC50: 12nMAssay Description:Inhibition of Aurora Kinase C (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAurora kinase C(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660655BDBM50660655(CHEMBL6167281)
Affinity DataIC50: 15nMAssay Description:Inhibition of Aurora Kinase C (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660652BDBM50660652(CHEMBL6161653)
Affinity DataIC50: 16nMAssay Description:Inhibition of TrkC (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660647BDBM50660647(CHEMBL6145514)
Affinity DataIC50: 16nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660659BDBM50660659(CHEMBL6142750)
Affinity DataIC50: 17nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660661BDBM50660661(CHEMBL6146464)
Affinity DataIC50: 18nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAurora kinase C(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660657BDBM50660657(CHEMBL6151974)
Affinity DataIC50: 20nMAssay Description:Inhibition of Aurora Kinase C (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660644BDBM50660644(CHEMBL6172073)
Affinity DataIC50: 20nMAssay Description:Inhibition of TrkC (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660663BDBM50660663(CHEMBL6172244)
Affinity DataIC50: 21nMAssay Description:Inhibition of ALK1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMothers against decapentaplegic homolog 3(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660663BDBM50660663(CHEMBL6172244)
Affinity DataIC50: 22nMAssay Description:Inhibition of TGFbeta-stimulated SMAD3 phosphorylation in human A549 cells preincubated for 1 hrs followed by human TGF-beta1 addition and measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660654BDBM50660654(CHEMBL6173813)
Affinity DataIC50: 24nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660662BDBM50660662(CHEMBL6170974)
Affinity DataIC50: 25nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660655BDBM50660655(CHEMBL6167281)
Affinity DataIC50: 26nMAssay Description:Inhibition of TrkC (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660660BDBM50660660(CHEMBL6143807)
Affinity DataIC50: 29nMAssay Description:Inhibition of TrkC (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAurora kinase C(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660651BDBM50660651(CHEMBL6167230)
Affinity DataIC50: 29nMAssay Description:Inhibition of Aurora Kinase C (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660645BDBM50660645(CHEMBL6168217)
Affinity DataIC50: 29nMAssay Description:Inhibition of TrkC (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAurora kinase C(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660654BDBM50660654(CHEMBL6173813)
Affinity DataIC50: 31nMAssay Description:Inhibition of Aurora Kinase C (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660664BDBM50660664(CHEMBL6163758)
Affinity DataIC50: 32nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660656BDBM50660656(CHEMBL6169687)
Affinity DataIC50: 35nMAssay Description:Inhibition of TrkC (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetActivin receptor type-1B(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660663BDBM50660663(CHEMBL6172244)
Affinity DataIC50: 35nMAssay Description:Inhibition of ALK4 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660650BDBM50660650(CHEMBL6169657)
Affinity DataIC50: 42nMAssay Description:Inhibition of TrkC (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAurora kinase C(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660653BDBM50660653(CHEMBL6166782)
Affinity DataIC50: 42nMAssay Description:Inhibition of Aurora Kinase C (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660658BDBM50660658(CHEMBL6169764)
Affinity DataIC50: 43nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660649BDBM50660649(CHEMBL6165023)
Affinity DataIC50: 45nMAssay Description:Inhibition of TrkC (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660661BDBM50660661(CHEMBL6146464)
Affinity DataIC50: 49nMAssay Description:Inhibition of TrkC (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660664BDBM50660664(CHEMBL6163758)
Affinity DataIC50: 50nMAssay Description:Inhibition of TrkC (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660646BDBM50660646(CHEMBL6165210)
Affinity DataIC50: 54nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660662BDBM50660662(CHEMBL6170974)
Affinity DataIC50: 59nMAssay Description:Inhibition of TrkC (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAurora kinase C(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660661BDBM50660661(CHEMBL6146464)
Affinity DataIC50: 61nMAssay Description:Inhibition of Aurora Kinase C (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660646BDBM50660646(CHEMBL6165210)
Affinity DataIC50: 63nMAssay Description:Inhibition of TrkC (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660663BDBM50660663(CHEMBL6172244)
Affinity DataIC50: 65nMAssay Description:Inhibition of ALK2 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660654BDBM50660654(CHEMBL6173813)
Affinity DataIC50: 69nMAssay Description:Inhibition of TrkC (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50015640BDBM50015640(LY-2157299 | GALUNISERTIB)
Affinity DataIC50: 75nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660663BDBM50660663(CHEMBL6172244)
Affinity DataIC50: 76nMAssay Description:Inhibition of TrkC (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660653BDBM50660653(CHEMBL6166782)
Affinity DataIC50: 80nMAssay Description:Inhibition of TrkC (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
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