Compile Data Set for Download or QSAR
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Found 11 Enz. Inhib. hit(s) with all data for entry = 50003316
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50026389(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-ami...)
Affinity DataKi:  0.00400nMAssay Description:In vitro inhibitory activity against Dihydrofolate reductase in L1210 cell in miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50026392(2-[3-(2-Carboxy-2-{4-[(2,4-diamino-pteridin-6-ylme...)
Affinity DataKi:  0.00471nMAssay Description:In vitro inhibitory activity against Dihydrofolate reductase in L1210 cell in miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50026399(3-(4-Chloro-benzoylamino)-2-{4-[(2,4-diamino-pteri...)
Affinity DataKi:  0.00498nMAssay Description:In vitro inhibitory activity against Dihydrofolate reductase in L1210 cell in miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50026391(5-(4-Chloro-benzoylamino)-2-{4-[(2,4-diamino-pteri...)
Affinity DataKi:  0.00531nMAssay Description:In vitro inhibitory activity against Dihydrofolate reductase in L1210 cell in miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataKi:  0.00581nMAssay Description:In vitro inhibitory activity against Dihydrofolate reductase in L1210 cell in miceMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataKi:  0.00600nMAssay Description:In vitro inhibitory activity against Dihydrofolate reductase in L1210 cell in miceMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50026402(4-(4-Chloro-benzoylamino)-2-{4-[(2,4-diamino-pteri...)
Affinity DataKi:  0.00642nMAssay Description:In vitro inhibitory activity against Dihydrofolate reductase in L1210 cell in miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50026401(2--[3-(2-Carboxy-2-{4-[(2,4-diamino-pteridin-6-ylm...)
Affinity DataKi:  3.24nMAssay Description:In vitro inhibitory activity against Dihydrofolate reductase in L1210 cell in miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50026390(2--[3-(2-Carboxy-2-{4-[(2,4-diamino-pteridin-6-ylm...)
Affinity DataKi:  6.35nMAssay Description:In vitro inhibitory activity against Dihydrofolate reductase in L1210 cell in miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50026398(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-ami...)
Affinity DataKi:  14nMAssay Description:In vitro inhibitory activity against Dihydrofolate reductase in L1210 cell in miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50026394(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-ami...)
Affinity DataKi:  35nMAssay Description:In vitro inhibitory activity against Dihydrofolate reductase in L1210 cell in miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed