Compile Data Set for Download or QSAR
Report error Found 51 Enz. Inhib. hit(s) with all data for entry = 50023768
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668014BDBM50668014(CHEMBL6190383)
Affinity DataEC50:  1nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667992BDBM50667992(CHEMBL6190154)
Affinity DataEC50:  1.5nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668013BDBM50668013(CHEMBL6193060)
Affinity DataEC50:  2nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668021BDBM50668021(CHEMBL6191562)
Affinity DataEC50:  2.5nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667999BDBM50667999(CHEMBL6193273)
Affinity DataEC50:  4.70nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668017BDBM50668017(CHEMBL6193148)
Affinity DataEC50:  5.30nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135482BDBM50135482(1-(5-Methoxy-2-thiophen-2-yl-quinazolin-4-ylamino)...)
Affinity DataEC50:  5.90nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668009BDBM50668009(CHEMBL6191512)
Affinity DataEC50:  7.10nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668020BDBM50668020(CHEMBL6192152)
Affinity DataEC50:  7.30nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668005BDBM50668005(CHEMBL6190954)
Affinity DataEC50:  8.30nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667994BDBM50667994(CHEMBL6190228)
Affinity DataEC50:  9nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667996BDBM50667996(CHEMBL6192172)
Affinity DataEC50:  9.40nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668018BDBM50668018(CHEMBL6193465)
Affinity DataEC50:  9.70nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668019BDBM50668019(CHEMBL6192106)
Affinity DataEC50:  11nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668006BDBM50668006(CHEMBL6190907)
Affinity DataEC50:  11nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668000BDBM50668000(CHEMBL6191853)
Affinity DataEC50:  12nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668007BDBM50668007(CHEMBL6189754)
Affinity DataEC50:  13nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667997BDBM50667997(CHEMBL6191728)
Affinity DataEC50:  18nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668015BDBM50668015(CHEMBL6193008)
Affinity DataEC50:  20nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668008BDBM50668008(CHEMBL6191609)
Affinity DataEC50:  23nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668016BDBM50668016(CHEMBL6193449)
Affinity DataEC50:  25nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668037BDBM50668037(CHEMBL6192966)
Affinity DataEC50:  29nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668034BDBM50668034(CHEMBL6188931)
Affinity DataEC50:  30nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668024BDBM50668024(CHEMBL6193567)
Affinity DataEC50:  31nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668031BDBM50668031(CHEMBL6191061)
Affinity DataEC50:  34nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668004BDBM50668004(CHEMBL6189888)
Affinity DataEC50:  37nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668011BDBM50668011(CHEMBL6192681)
Affinity DataEC50:  40nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668022BDBM50668022(CHEMBL6190611)
Affinity DataEC50:  45nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668012BDBM50668012(CHEMBL6190507)
Affinity DataEC50:  46nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668029BDBM50668029(CHEMBL6189249)
Affinity DataEC50:  58nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668010BDBM50668010(CHEMBL6188349)
Affinity DataEC50:  60nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668036BDBM50668036(CHEMBL6188947)
Affinity DataEC50:  60nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667998BDBM50667998(CHEMBL6190707)
Affinity DataEC50:  61nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668035BDBM50668035(CHEMBL6190692)
Affinity DataEC50:  62nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668027BDBM50668027(CHEMBL6188683)
Affinity DataEC50:  66nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668023BDBM50668023(CHEMBL6193569)
Affinity DataEC50:  76nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668038BDBM50668038(CHEMBL6191712)
Affinity DataEC50:  80nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668039BDBM50668039(CHEMBL6191546)
Affinity DataEC50:  96nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668025BDBM50668025(CHEMBL6189682)
Affinity DataEC50:  107nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667993BDBM50667993(CHEMBL6190005)
Affinity DataEC50:  156nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668026BDBM50668026(CHEMBL6191214)
Affinity DataEC50:  170nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668033BDBM50668033(CHEMBL6188699)
Affinity DataEC50:  209nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668032BDBM50668032(CHEMBL6192032)
Affinity DataEC50:  222nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668030BDBM50668030(CHEMBL6191367)
Affinity DataEC50:  250nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668040BDBM50668040(CHEMBL6189596)
Affinity DataEC50:  251nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668003BDBM50668003(CHEMBL6189477)
Affinity DataEC50:  447nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668041BDBM50668041(CHEMBL6189359)
Affinity DataEC50:  550nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668001BDBM50668001(CHEMBL6189431)
Affinity DataEC50:  724nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668028BDBM50668028(CHEMBL6189532)
Affinity DataEC50:  963nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetExportin-1(Human)
Case Western Reserve University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668002BDBM50668002(CHEMBL6188576)
Affinity DataEC50:  1.63E+3nMAssay Description:Inhibition of XPO1 in PMA/ionomycin-activated human Jurkat cells expressing IL-2 promoter reporter gene assessed as suppression of IL-2 transcription...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
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