Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50000458
TargetC-X-C chemokine receptor type 4(Human)
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250705(CHEMBL4078698)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 4(Human)
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250733(CHEMBL4064373)
Affinity DataIC50:  6nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 4(Human)
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250704(CHEMBL4089168)
Affinity DataIC50:  6nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 4(Human)
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250704(CHEMBL4089168)
Affinity DataIC50:  20nMAssay Description:Displacement of [125I]-CXCL12 from CXCR4 in human CCRF-CEM cells after 1 hr by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 4(Human)
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250710(CHEMBL4061034)
Affinity DataIC50:  22nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 4(Human)
University of Campania

Curated by ChEMBL
LigandPNGBDBM50192468(CHEMBL3923282)
Affinity DataIC50:  40nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 4(Human)
University of Campania

Curated by ChEMBL
LigandPNGBDBM50192652(CHEMBL3901189)
Affinity DataIC50:  53nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 4(Human)
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250721(CHEMBL4093767)
Affinity DataIC50:  70nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 4(Human)
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250732(CHEMBL4064578)
Affinity DataIC50:  180nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 4(Human)
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250711(CHEMBL4065967)
Affinity DataIC50:  210nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 4(Human)
University of Campania

Curated by ChEMBL
LigandPNGBDBM50192468(CHEMBL3923282)
Affinity DataIC50:  338nMAssay Description:Displacement of [125I]-CXCL12 from CXCR4 in human CCRF-CEM cells after 1 hr by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 4(Human)
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250709(CHEMBL4076358)
Affinity DataIC50:  360nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 4(Human)
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250708(CHEMBL4079246)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 4(Human)
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250723(CHEMBL4060078)
Affinity DataIC50:  1.53E+3nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 4(Human)
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250706(CHEMBL4096721)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 4(Human)
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250725(CHEMBL4073066)
Affinity DataIC50:  2.14E+3nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 4(Human)
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250724(CHEMBL4074277)
Affinity DataIC50:  3.69E+3nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 4(Human)
University of Campania

Curated by ChEMBL
LigandPNGBDBM50035696(1,1''-{1,4-phenylenebis(methylene)}-bis{1,4,8,11-t...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetC-X-C chemokine receptor type 4(Human)
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250722(CHEMBL4087597)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 4(Human)
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250731(CHEMBL4091892)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetC-X-C chemokine receptor type 4(Human)
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250707(CHEMBL4104439)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed