Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50028873
LigandPNGBDBM50008064(CHEMBL37132 | 3-Ethyl-4-(3-methyl-3H-imidazol-4-yl...)
Affinity DataIC50: 43nMAssay Description:Compound was evaluated for its ability to displace muscarinic agonist [3H]quinuclidinyl benzilate in rat cortical tissue (RCMD binding assay), at 0.1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50004665(1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...)
Affinity DataIC50: 360nMAssay Description:Compound was evaluated for the displacement of the muscarinic QNB in a genetically transformed rat cell line (m1c2) transfected with cloned m1 recept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50004665(1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...)
Affinity DataIC50: 860nMAssay Description:Compound was evaluated for the displacement of the muscarinic QNB in rat heart homogenate containing the pharmacologic M2 receptor (M2-QNB heart)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50008072((3S-cis)-3-ethyldihydro-4-[(1-methyl-1H-imidazol-5...)
Affinity DataIC50: 4.43E+3nMAssay Description:Compound was evaluated for the displacement of the muscarinic QNB in a genetically transformed rat cell line (m1c2) transfected with cloned m1 recept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50008072((3S-cis)-3-ethyldihydro-4-[(1-methyl-1H-imidazol-5...)
Affinity DataIC50: 8.80E+3nMAssay Description:Compound was evaluated for the displacement of the muscarinic QNB in rat heart homogenate containing the pharmacologic M2 receptor (M2-QNB heart)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50008064(CHEMBL37132 | 3-Ethyl-4-(3-methyl-3H-imidazol-4-yl...)
Affinity DataIC50: 8.90E+3nMAssay Description:Compound was evaluated for its ability to displace muscarinic antagonist [3H]cis-methyldioxolane in rat cortical tissue (RQNB binding assay), at 1.0 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM46858(cid_9301 | ARECOLINE HYDROBROMIDE | SMR000058258 |...)
Affinity DataIC50: 9.15E+3nMAssay Description:Compound was evaluated for the displacement of the muscarinic QNB in rat heart homogenate containing the pharmacologic M2 receptor (M2-QNB heart)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM46858(cid_9301 | ARECOLINE HYDROBROMIDE | SMR000058258 |...)
Affinity DataIC50: 1.19E+4nMAssay Description:Compound was evaluated for the displacement of the muscarinic QNB in a genetically transformed rat cell line (m1c2) transfected with cloned m1 recept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50008064(CHEMBL37132 | 3-Ethyl-4-(3-methyl-3H-imidazol-4-yl...)
Affinity DataIC50: 1.27E+4nMAssay Description:Compound was evaluated for the displacement of the muscarinic QNB in a genetically transformed rat cell line (m1c2) transfected with cloned m1 recept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50004656((2-Hydroxyethyl)trimethyl ammonium chloride carbam...)
Affinity DataIC50: 1.89E+4nMAssay Description:Compound was evaluated for the displacement of the muscarinic QNB in rat heart homogenate containing the pharmacologic M2 receptor (M2-QNB heart)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50008064(CHEMBL37132 | 3-Ethyl-4-(3-methyl-3H-imidazol-4-yl...)
Affinity DataIC50: 3.09E+4nMAssay Description:Compound was evaluated for the displacement of the muscarinic QNB in rat heart homogenate containing the pharmacologic M2 receptor (M2-QNB heart)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50004656((2-Hydroxyethyl)trimethyl ammonium chloride carbam...)
Affinity DataIC50: 4.44E+4nMAssay Description:Compound was evaluated for the displacement of the muscarinic QNB in a genetically transformed rat cell line (m1c2) transfected with cloned m1 recept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50211667(CHEMBL37008)
Affinity DataIC50: 7.30E+4nMAssay Description:Compound was evaluated for its ability to displace muscarinic agonist [3H]quinuclidinyl benzilate in rat cortical tissue (RCMD binding assay), at 0.1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50211667(CHEMBL37008)
Affinity DataIC50: 3.30E+6nMAssay Description:Compound was evaluated for its ability to displace muscarinic antagonist [3H]cis-methyldioxolane in rat cortical tissue (RQNB binding assay), at 1.0 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article