Compile Data Set for Download or QSAR
maximum 50k data
Found 11 Enz. Inhib. hit(s) with all data for entry = 50028986
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM22971(2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...)
Affinity DataIC50:  100nMAssay Description:Binding affinity at 5-hydroxytryptamine 3 receptor in rat posterior cortex by [3H]-BRL 43694 displacement.More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  500nMAssay Description:Concentration of the compound required to inhibit dog plasma renin by 50% using radio-immunoassay was determinedMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280512(5-[1-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl...)
Affinity DataIC50:  820nMAssay Description:Compound was evaluated for its inhibitory activity against 5-LO(5-lipoxygenase)More data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280511(5-[1-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-i...)
Affinity DataIC50:  1.40E+3nMAssay Description:Compound was evaluated for its inhibitory activity against 5-LO(5-lipoxygenase) in intact RBL-1 cell line assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280514(5-[1-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl...)
Affinity DataIC50:  1.50E+3nMAssay Description:Compound was evaluated for its inhibitory activity against 5-LO(5-lipoxygenase) in intact RBL-1 cell line assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50280511(5-[1-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-i...)
Affinity DataIC50:  2.00E+3nMAssay Description:Antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor in isolated rabbit vagus nerve (RVN)More data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280513(CHEMBL350341 | {5-[1-[2-(2,6-Dichloro-3-methyl-phe...)
Affinity DataIC50:  2.20E+3nMAssay Description:Compound was evaluated for its inhibitory activity against 5-LO(5-lipoxygenase) in intact RBL-1 cell line assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50280512(5-[1-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl...)
Affinity DataIC50:  6.00E+3nMAssay Description:Antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor in isolated rabbit vagus nerve (RVN)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50280514(5-[1-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl...)
Affinity DataIC50:  1.02E+4nMAssay Description:Antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor of isolated guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM22971(2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...)
Affinity DataIC50:  2.40E+4nMAssay Description:Compound was evaluated for its inhibitory activity against 5-LO(5-lipoxygenase)More data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for its inhibitory activity against 5-LO(5-lipoxygenase) in intact RBL-1 cell line assayMore data for this Ligand-Target Pair
In DepthDetails Article