Compile Data Set for Download or QSAR
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Found 25 Enz. Inhib. hit(s) with all data for entry = 50029046
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280965(4-Phenyl-7-(5-phenyl-pyridin-2-ylmethoxy)-3H-napht...)
Affinity DataIC50:  22nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280968(4-(3-Methoxy-phenyl)-3H-naphtho[2,3-c]furan-1-one ...)
Affinity DataIC50:  42nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280961(9-Benzo[1,3]dioxol-5-yl-8H-furo[3',4':6,7]naphtho[...)
Affinity DataIC50:  70nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280963(4-Phenyl-7-(quinolin-2-ylmethoxy)-3H-naphtho[2,3-c...)
Affinity DataIC50:  88nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280959(7-Benzyloxy-4-phenyl-3H-naphtho[2,3-c]furan-1-one ...)
Affinity DataIC50:  100nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280979(9-Phenyl-8H-furo[3',4':6,7]naphtho[2,3-d][1,3]diox...)
Affinity DataIC50:  160nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280962(7-Methoxy-4-phenyl-3H-naphtho[2,3-c]furan-1-one | ...)
Affinity DataIC50:  180nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280974(5-Benzo[1,3]dioxol-5-yl-6,8-dihydro-furo[3',4':6,7...)
Affinity DataIC50:  230nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280976(5-Benzo[1,3]dioxol-5-yl-6,7-dimethyl-naphtho[2,3-d...)
Affinity DataIC50:  250nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280966(4-Phenyl-3H-naphtho[2,3-c]furan-1-one | CHEMBL6189...)
Affinity DataIC50:  250nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280971(5-Benzo[1,3]dioxol-5-yl-8H-furo[3',4':6,7]naphtho[...)
Affinity DataIC50:  250nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280970(4-Benzo[1,3]dioxol-5-yl-3H-naphtho[2,3-c]furan-1-o...)
Affinity DataIC50:  380nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280967(5-Benzo[1,3]dioxol-5-yl-5,9-dihydro-furo[3',4':6,7...)
Affinity DataIC50:  420nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280977(4-Phenyl-5H-6-oxa-1-thia-s-indacen-7-one | CHEMBL6...)
Affinity DataIC50:  450nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280961(9-Benzo[1,3]dioxol-5-yl-8H-furo[3',4':6,7]naphtho[...)
Affinity DataIC50:  500nMAssay Description:Compound was evaluated in vitro for inhibition of human recombinant 5-lipoxygenase enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280964(5-Benzo[1,3]dioxol-5-yl-furo[3',4':6,7]naphtho[2,3...)
Affinity DataIC50:  660nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280978(6-Methoxy-4-phenyl-3H-naphtho[2,3-c]furan-1-one | ...)
Affinity DataIC50:  670nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50240576(4-Benzo[1,3]dioxol-5-yl-6,7-dimethoxy-3H-naphtho[2...)
Affinity DataIC50:  760nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280973(4-(4-Methoxy-phenyl)-3H-naphtho[2,3-c]furan-1-one ...)
Affinity DataIC50:  1.40E+3nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280975((5-Benzo[1,3]dioxol-5-yl-7-hydroxymethyl-naphtho[2...)
Affinity DataIC50:  2.20E+3nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280959(7-Benzyloxy-4-phenyl-3H-naphtho[2,3-c]furan-1-one ...)
Affinity DataIC50:  3.00E+3nMAssay Description:Compound was evaluated in vitro for inhibition of human recombinant lipoxygenase enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280969(4-Phenyl-3H-furo[3,4-g]isoquinolin-1-one | CHEMBL3...)
Affinity DataIC50:  3.80E+3nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280972(4-Pyridin-4-yl-3H-naphtho[2,3-c]furan-1-one | CHEM...)
Affinity DataIC50: >4.00E+3nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280980(9-Benzo[1,3]dioxol-5-yl-7,8-dihydro-1,3-dioxa-7-az...)
Affinity DataIC50:  4.20E+3nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280960(9-(3,4-Dimethoxy-phenyl)-8H-furo[3',4':6,7]naphtho...)
Affinity DataIC50: >5.00E+3nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article