Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50029074
TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000040BDBM50000040(CHEMBL16192 | (+)(2-Benzhydryl-1-aza-bicyclo[2.2.2...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50281196BDBM50281196((S)-Piperazine-1,2,4-tricarboxylic acid 4-dipentyl...)
Affinity DataIC50: 9nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50281189BDBM50281189((S)-Piperazine-1,2,4-tricarboxylic acid 4-dipentyl...)
Affinity DataIC50: 9nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50281194BDBM50281194((S)-Piperazine-1,2,4-tricarboxylic acid 2-[(2-diet...)
Affinity DataIC50: 11nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50281198BDBM50281198((S)-Piperazine-1,2,4-tricarboxylic acid 4-dipentyl...)
Affinity DataIC50: 17nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50281187BDBM50281187((S)-Piperazine-1,2,4-tricarboxylic acid 2-[(3-diet...)
Affinity DataIC50: 41nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50281200BDBM50281200((S)-Piperazine-1,2,4-tricarboxylic acid 2-[(2-dime...)
Affinity DataIC50: 55nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50281201BDBM50281201((S)-Piperazine-1,2,4-tricarboxylic acid 2-[(2-amin...)
Affinity DataIC50: 57nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50280912BDBM50280912(4-Dipentylcarbamoyl-1-diphenylcarbamoyl-piperazine...)
Affinity DataIC50: 130nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50281192BDBM50281192((S)-Piperazine-1,2,4-tricarboxylic acid 2-[(2-acet...)
Affinity DataIC50: 140nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50281193BDBM50281193((S)-Piperazine-1,2,4-tricarboxylic acid 2-({2-[(3,...)
Affinity DataIC50: 200nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50281191BDBM50281191((S)-Piperazine-1,2,4-tricarboxylic acid 2-[(2-diis...)
Affinity DataIC50: 217nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50281188BDBM50281188((S)-Piperazine-1,2,4-tricarboxylic acid 4-dipentyl...)
Affinity DataIC50: 267nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50280905BDBM50280905(4N,4N-dipentyl-1N,1N-diphenyl-2-hydroxymethyl-(2S)...)
Affinity DataIC50: 280nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50281199BDBM50281199((S)-Piperazine-1,2,4-tricarboxylic acid 2-{[2-(ben...)
Affinity DataIC50: 290nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50280915BDBM50280915(1N,1N-dipentyl-4N,4N-diphenylhexahydro-1,4-pyrazin...)
Affinity DataIC50: 500nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50281195BDBM50281195([((S)-4-Dipentylcarbamoyl-1-diphenylcarbamoyl-pipe...)
Affinity DataIC50: 597nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50281190BDBM50281190((S)-Piperazine-1,2,4-tricarboxylic acid 2-[(2-dime...)
Affinity DataIC50: 930nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50281197BDBM50281197((S)-Piperazine-1,2,4-tricarboxylic acid 2-({2-[(3,...)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50280921BDBM50280921(4-dipentylcarbamoyl-1-diphenylcarbamoyl-(2R)-hexah...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article