Compile Data Set for Download or QSAR
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Found 20 Enz. Inhib. hit(s) with all data for entry = 50029074
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50000040(((2S,3S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281189((S)-Piperazine-1,2,4-tricarboxylic acid 4-dipentyl...)
Affinity DataIC50:  9nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281196((S)-Piperazine-1,2,4-tricarboxylic acid 4-dipentyl...)
Affinity DataIC50:  9nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281194((S)-Piperazine-1,2,4-tricarboxylic acid 2-[(2-diet...)
Affinity DataIC50:  11nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281198((S)-Piperazine-1,2,4-tricarboxylic acid 4-dipentyl...)
Affinity DataIC50:  17nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281187((S)-Piperazine-1,2,4-tricarboxylic acid 2-[(3-diet...)
Affinity DataIC50:  41nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281200((S)-Piperazine-1,2,4-tricarboxylic acid 2-[(2-dime...)
Affinity DataIC50:  55nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281201((S)-Piperazine-1,2,4-tricarboxylic acid 2-[(2-amin...)
Affinity DataIC50:  57nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280912((S)-4-Dipentylcarbamoyl-1-diphenylcarbamoyl-pipera...)
Affinity DataIC50:  130nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281192((S)-Piperazine-1,2,4-tricarboxylic acid 2-[(2-acet...)
Affinity DataIC50:  140nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281193((S)-Piperazine-1,2,4-tricarboxylic acid 2-({2-[(3,...)
Affinity DataIC50:  200nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281191((S)-Piperazine-1,2,4-tricarboxylic acid 2-[(2-diis...)
Affinity DataIC50:  217nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281188((S)-Piperazine-1,2,4-tricarboxylic acid 4-dipentyl...)
Affinity DataIC50:  267nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280905((S)-2-Hydroxymethyl-piperazine-1,4-dicarboxylic ac...)
Affinity DataIC50:  280nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281199((S)-Piperazine-1,2,4-tricarboxylic acid 2-{[2-(ben...)
Affinity DataIC50:  290nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280915(1N,1N-dipentyl-4N,4N-diphenylhexahydro-1,4-pyrazin...)
Affinity DataIC50:  500nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281195(CHEMBL90035 | [((S)-4-Dipentylcarbamoyl-1-diphenyl...)
Affinity DataIC50:  597nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281190((S)-Piperazine-1,2,4-tricarboxylic acid 2-[(2-dime...)
Affinity DataIC50:  930nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281197((S)-Piperazine-1,2,4-tricarboxylic acid 2-({2-[(3,...)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280921((R)-4-Dipentylcarbamoyl-1-diphenylcarbamoyl-pipera...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of [125I]-Substance P binding to human NK1 receptors in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article