Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 50029112
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281579((S)-3-{2-[((R)-2-Acetylamino-3-phenyl-propionyl)-b...)
Affinity DataIC50:  12nMAssay Description:Inhibition of [125I]-ET-1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281586((R)-3-{[(R)-1-((R)-2-Acetylamino-3-phenyl-propiony...)
Affinity DataIC50:  15nMAssay Description:The inhibitory constant of the compound was evaluated against Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281576((S)-3-{(S)-2-[(R)-2-Acetylamino-3-(1H-indol-3-yl)-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of [125I]-ET-1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281577((S)-3-{(S)-2-[(R)-2-Acetylamino-3-(4-hydroxy-pheny...)
Affinity DataIC50:  26nMAssay Description:Inhibition of [125I]-ET-1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281579((S)-3-{2-[((R)-2-Acetylamino-3-phenyl-propionyl)-b...)
Affinity DataIC50:  30nMAssay Description:The inhibitory constant of the compound was evaluated against Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281586((R)-3-{[(R)-1-((R)-2-Acetylamino-3-phenyl-propiony...)
Affinity DataIC50:  45nMAssay Description:Inhibition of [125I]-ET-1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281580((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50:  57nMAssay Description:Inhibition of [125I]-ET-1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281581((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50:  70nMAssay Description:Inhibition of [125I]-ET-1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281582((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50:  75nMAssay Description:Inhibition of [125I]-ET-1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281575((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50:  77nMAssay Description:Inhibition of [125I]-ET-1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281585((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50:  79nMAssay Description:Inhibition of [125I]-ET-1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281587((S)-3-[(R)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50:  98nMAssay Description:Inhibition of [125I]-ET-1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281583((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50:  114nMAssay Description:Inhibition of [125I]-ET-1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281576((S)-3-{(S)-2-[(R)-2-Acetylamino-3-(1H-indol-3-yl)-...)
Affinity DataIC50:  130nMAssay Description:The inhibitory constant of the compound was evaluated against Endothelin A receptor in rabbit renal artery tissueMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281584((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50:  230nMAssay Description:The compound was tested for the binding affinity against eEndothelin A receptor in murine 3T3 cells using [125I]-ET-1 as a radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281578((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50:  270nMAssay Description:Inhibition of [125I]-ET-1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281577((S)-3-{(S)-2-[(R)-2-Acetylamino-3-(4-hydroxy-pheny...)
Affinity DataIC50:  400nMAssay Description:The inhibitory constant of the compound was evaluated against Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281584((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50: <800nMAssay Description:The inhibitory constant was evaluated against Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article