Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50029305
LigandChemical structure of BindingDB Monomer ID 50283128BDBM50283128(5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1,2-dimethyl...)
Affinity DataIC50: 5nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]pirenzepine in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50283129BDBM50283129(5-(4-Hex-3-ynyloxy-[1,2,5]thiadiazol-3-yl)-1,2-dim...)
Affinity DataIC50: 5nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]pirenzepine in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50283130BDBM50283130(1,2-Dimethyl-5-(4-pentyloxy-[1,2,5]thiadiazol-3-yl...)
Affinity DataIC50: 5nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]pirenzepine in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50283129BDBM50283129(5-(4-Hex-3-ynyloxy-[1,2,5]thiadiazol-3-yl)-1,2-dim...)
Affinity DataIC50: 6nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]oxotremorine-M in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50283128BDBM50283128(5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1,2-dimethyl...)
Affinity DataIC50: 6nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]oxotremorine-M in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50003359BDBM50003359(CHEMBL73149 | LY 246708 | CHEMBL21536 | 5-(4-Hexyl...)
Affinity DataIC50: 7nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]pirenzepine in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50283138BDBM50283138(5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1,3-dimethyl...)
Affinity DataIC50: 7nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]pirenzepine in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50283137BDBM50283137(5-(4-Butoxy-[1,2,5]thiadiazol-3-yl)-1,2-dimethyl-1...)
Affinity DataIC50: 8nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]pirenzepine in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50283137BDBM50283137(5-(4-Butoxy-[1,2,5]thiadiazol-3-yl)-1,2-dimethyl-1...)
Affinity DataIC50: 8nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]pirenzepine in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50283130BDBM50283130(1,2-Dimethyl-5-(4-pentyloxy-[1,2,5]thiadiazol-3-yl...)
Affinity DataIC50: 9nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]oxotremorine-M in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50283131BDBM50283131(1,2-Dimethyl-5-(4-pent-4-enyloxy-[1,2,5]thiadiazol...)
Affinity DataIC50: 10nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]oxotremorine-M in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50003359BDBM50003359(CHEMBL73149 | LY 246708 | CHEMBL21536 | 5-(4-Hexyl...)
Affinity DataIC50: 10nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]oxotremorine-M in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50283131BDBM50283131(1,2-Dimethyl-5-(4-pent-4-enyloxy-[1,2,5]thiadiazol...)
Affinity DataIC50: 10nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]oxotremorine-M in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50283135BDBM50283135(5-(4-Ethoxy-[1,2,5]thiadiazol-3-yl)-1,2-dimethyl-1...)
Affinity DataIC50: 11nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]oxotremorine-M in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50283138BDBM50283138(5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1,3-dimethyl...)
Affinity DataIC50: 14nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]oxotremorine-M in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50283140BDBM50283140(1,3-Dimethyl-5-(4-propoxy-[1,2,5]thiadiazol-3-yl)-...)
Affinity DataIC50: 15nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]pirenzepine in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50283140BDBM50283140(1,3-Dimethyl-5-(4-propoxy-[1,2,5]thiadiazol-3-yl)-...)
Affinity DataIC50: 15nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]pirenzepine in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50003369BDBM50003369(CHEMBL308803 | CHEMBL303922 | 1-Methyl-5-(4-propox...)
Affinity DataIC50: 18nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]pirenzepine in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50003369BDBM50003369(CHEMBL308803 | CHEMBL303922 | 1-Methyl-5-(4-propox...)
Affinity DataIC50: 18nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]pirenzepine in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50003361BDBM50003361(5-(4-Methoxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2,...)
Affinity DataIC50: 22nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]oxotremorine-M in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50003361BDBM50003361(5-(4-Methoxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2,...)
Affinity DataIC50: 22nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]oxotremorine-M in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50283135BDBM50283135(5-(4-Ethoxy-[1,2,5]thiadiazol-3-yl)-1,2-dimethyl-1...)
Affinity DataIC50: 24nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]pirenzepine in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50283136BDBM50283136(5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1,6-dimethyl...)
Affinity DataIC50: 83nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]oxotremorine-M in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50283136BDBM50283136(5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1,6-dimethyl...)
Affinity DataIC50: 83nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]oxotremorine-M in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50283139BDBM50283139(5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1,4-dimethyl...)
Affinity DataIC50: 100nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]oxotremorine-M in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50283139BDBM50283139(5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1,4-dimethyl...)
Affinity DataIC50: 112nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]pirenzepine in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50283132BDBM50283132(5-(4-Methoxy-[1,2,5]thiadiazol-3-yl)-1,3-dimethyl-...)
Affinity DataIC50: 580nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]pirenzepine in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50283132BDBM50283132(5-(4-Methoxy-[1,2,5]thiadiazol-3-yl)-1,3-dimethyl-...)
Affinity DataIC50: 600nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]oxotremorine-M in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50283133BDBM50283133(5-(4-Methoxy-[1,2,5]thiadiazol-3-yl)-1,4-dimethyl-...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]oxotremorine-M in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50283133BDBM50283133(5-(4-Methoxy-[1,2,5]thiadiazol-3-yl)-1,4-dimethyl-...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]pirenzepine in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50283134BDBM50283134(3-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1,4a,8a-trim...)
Affinity DataIC50: 1.23E+3nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]pirenzepine in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50283134BDBM50283134(3-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1,4a,8a-trim...)
Affinity DataIC50: 1.23E+3nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]pirenzepine in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article