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Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50029349
TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283623((1S,3S,4S,5R,6R,7R)-6-((E)-4,6-Dimethyl-oct-2-enoy...)
Affinity DataIC50:  5nMAssay Description:Inhibitory concentration against mammalian Squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50051873((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  12nMAssay Description:Inhibitory concentration against mammalian Squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePDB3D3D Structure (crystal)

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50051872((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  26nMAssay Description:Inhibitory concentration against mammalian Squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283615((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Allyloxy-5-methyl...)
Affinity DataIC50:  27nMAssay Description:Inhibitory concentration against mammalian Squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283618((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Cyclopropylmethox...)
Affinity DataIC50:  33nMAssay Description:Inhibitory concentration against mammalian Squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283616((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Ethoxy-5-methyl-3...)
Affinity DataIC50:  40nMAssay Description:Inhibitory concentration against mammalian Squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283614((1S,3S,4S,5R,6R,7R)-4,6,7-Trihydroxy-1-((4S,5R)-4-...)
Affinity DataIC50:  49nMAssay Description:Inhibitory concentration against mammalian Squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283626((1S,3S,4S,5R,6R,7R)-4,6,7-Trihydroxy-1-((4S,5R)-4-...)
Affinity DataIC50:  252nMAssay Description:Inhibitory concentration against mammalian Squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283629((1S,3S,4S,5R,6R,7R)-4,6,7-Trihydroxy-1-((4S,5R)-4-...)
Affinity DataIC50:  500nMAssay Description:Inhibitory concentration against mammalian Squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283619((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Benzoyloxy-5-meth...)
Affinity DataIC50:  532nMAssay Description:Inhibitory concentration against mammalian Squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283622((1S,3S,4S,5R,6R,7R)-4,6,7-Trihydroxy-1-((4S,5R)-5-...)
Affinity DataIC50:  600nMAssay Description:Inhibitory concentration against mammalian Squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283621((1S,3S,4S,5R,6R,7R)-4,6,7-Trihydroxy-1-((4S,5R)-5-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory concentration against mammalian Squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283628((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Benzyloxy-5-methy...)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibitory concentration against mammalian Squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283617((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetylamino-5-met...)
Affinity DataIC50:  2.23E+3nMAssay Description:Inhibitory concentration against mammalian Squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283620((1S,3S,4S,5R,6R,7R)-1-[(4S,5R)-4-(2,2-Dimethyl-pro...)
Affinity DataIC50:  2.29E+3nMAssay Description:Inhibitory concentration against mammalian Squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283627((1S,3S,4S,5R,6R,7R)-1-[(Z)-(S)-3-(Acetylamino-meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against mammalian Squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283625((1S,3S,4S,5R,6R,7R)-1-[(Z)-(R)-3-(Acetylamino-meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against mammalian Squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283624((1S,3S,4S,5R,6R,7R)-1-((4R,5R)-4-Acetylamino-5-met...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against mammalian Squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article