Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50029379
TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50034851(CGS-24592 | diphenyl alpha -aminomethyl phosphonat...)
Affinity DataIC50: 1.60nMAssay Description:In vitro inhibitory activity against neutral endopeptidase (NEP 24.11) from rat kidney cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM21641(2-(2-benzyl-3-sulfanylpropanamido)acetic acid | CH...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory activity against neutral endopeptidase (NEP 24.11) from rat kidney cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283970(3-(3-Biphenyl-4-yl-2-phosphonomethoxy-propionylami...)
Affinity DataIC50: 9.5nMAssay Description:In vitro inhibitory activity against neutral endopeptidase (NEP 24.11) from rat kidney cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283968(3-(3-Biphenyl-4-yl-2-phosphonomethylsulfanyl-propi...)
Affinity DataIC50: 797nMAssay Description:In vitro inhibitory activity against neutral endopeptidase (NEP 24.11) from rat kidney cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283969(3-(2-Biphenyl-4-ylmethyl-4-phosphono-butyrylamino)...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory activity against neutral endopeptidase (NEP 24.11) from rat kidney cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283967(3-(3-Biphenyl-4-yl-2-phosphonomethanesulfonyl-prop...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against neutral endopeptidase (NEP 24.11) from rat kidney cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article