Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50029451
TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000041BDBM50000041((+/-)(2-Methoxy-benzyl)-(2-phenyl-piperidin-3-yl)-...)
Affinity DataIC50: 0.5nMAssay Description:Binding affinity towards Neurokinin -1(NK-1) receptor of human by using [125I]- Tyr8 substance P as a radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50154572BDBM50154572(2-[1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2,2...)
Affinity DataIC50: 0.850nMAssay Description:Binding affinity towards Neurokinin -1(NK-1) receptor of human by using [125I]- Tyr8 substance P as a radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049468BDBM50049468((2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-ph...)
Affinity DataIC50: 1nMAssay Description:Binding affinity towards Neurokinin -1(NK-1) receptor of human by using [125I]- Tyr8 substance P as a radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052283BDBM50052283(2-[3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-...)
Affinity DataIC50: 1nMAssay Description:Binding affinity towards Neurokinin -1(NK-1) receptor of human by using [125I]- Tyr8 substance P as a radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50284636BDBM50284636(2-[3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-...)
Affinity DataIC50: 1.5nMAssay Description:Binding affinity towards Neurokinin -1(NK-1) receptor of human by using [125I]- Tyr8 substance P as a radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50284636BDBM50284636(2-[3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-...)
Affinity DataIC50: 1.5nMAssay Description:Binding affinity towards Neurokinin -1(NK-1) receptor of human by using [125I]- Tyr8 substance P as a radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50284633BDBM50284633(2-[3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-...)
Affinity DataIC50: 3.70nMAssay Description:Binding affinity towards Neurokinin -1(NK-1) receptor of human by using [125I]- Tyr8 substance P as a radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50284639BDBM50284639([3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-cy...)
Affinity DataIC50: 6.70nMAssay Description:Binding affinity towards Neurokinin -1(NK-1) receptor of human by using [125I]- Tyr8 substance P as a radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50284634BDBM50284634(2-[3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-...)
Affinity DataIC50: 7nMAssay Description:Binding affinity towards Neurokinin -1(NK-1) receptor of human by using [125I]- Tyr8 substance P as a radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50154571BDBM50154571(1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2,2-di...)
Affinity DataIC50: 10.7nMAssay Description:Binding affinity towards Neurokinin -1(NK-1) receptor of human by using [125I]- Tyr8 substance P as a radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50284632BDBM50284632(3-(3,5-Bis-trifluoromethyl-benzyloxy)-1-methyl-2-p...)
Affinity DataIC50: 14nMAssay Description:Binding affinity towards Neurokinin -1(NK-1) receptor of human by using [125I]- Tyr8 substance P as a radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50284640BDBM50284640(3-(3,5-Bis-trifluoromethyl-benzyloxy)-1,1-diphenyl...)
Affinity DataIC50: 17nMAssay Description:Binding affinity towards Neurokinin -1(NK-1) receptor of human by using [125I]- Tyr8 substance P as a radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50284637BDBM50284637(1-[3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-...)
Affinity DataIC50: 34nMAssay Description:Binding affinity towards Neurokinin -1(NK-1) receptor of human by using [125I]- Tyr8 substance P as a radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50284635BDBM50284635(3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-tet...)
Affinity DataIC50: 881nMAssay Description:Binding affinity towards Neurokinin -1(NK-1) receptor of human by using [125I]- Tyr8 substance P as a radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50284638BDBM50284638(1-((1S,2S)-2-Phenyl-cyclohexyloxymethyl)-3,5-bis-t...)
Affinity DataIC50: 2.63E+3nMAssay Description:Binding affinity towards Neurokinin -1(NK-1) receptor of human by using [125I]- Tyr8 substance P as a radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article