Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with all data for entry = 50029536
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50066068(CHEMBL28853 | N-Acenaphthen-5-yl-N'-(4-methoxy-nap...)
Affinity DataIC50:  1.31E+3nMAssay Description:Blockade of synaptosomal sodium channels, inhibition of [14C]-guanidinium ion flux into CHO cells expressing Type II sodium channelMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285278(CHEMBL307395 | N,N'-Di-acenaphthen-5-yl-guanidine)
Affinity DataIC50:  2.03E+3nMAssay Description:Blockade of synaptosomal sodium channels, inhibition of [14C]-guanidinium ion flux into CHO cells expressing Type II sodium channelMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM30705(CHEMBL744 | MLS000069369 | RILUZOLE | SMR000058231...)
Affinity DataIC50:  2.20E+3nMAssay Description:Blockade of synaptosomal sodium channels, inhibition of [14C]-guanidinium ion flux into CHO cells expressing Type II sodium channelMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50066430(2-(4-Methyl-piperazin-1-yl)-5-(2,3,5-trichloro-phe...)
Affinity DataIC50:  2.55E+3nMAssay Description:Blockade of synaptosomal sodium channels, inhibition of [14C]-guanidinium ion flux into CHO cells expressing Type II sodium channelMore data for this Ligand-Target Pair
In DepthDetails Article