Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 50029802
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024096(((R)-2-Mercaptomethyl-3-phenyl-propionylamino)-ace...)
Affinity DataKi:  1.70nMAssay Description:Compound was evaluated for inhibition of recombinant human neprilysin(NEP).More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024102(((S)-2-Mercaptomethyl-3-phenyl-propionylamino)-ace...)
Affinity DataKi:  2.20nMAssay Description:Compound was evaluated for inhibition of recombinant human neprilysin(NEP).More data for this Ligand-Target Pair
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM21641(2-(2-benzyl-3-sulfanylpropanamido)acetic acid | CH...)
Affinity DataKi:  4.70nMAssay Description:Compound was evaluated for inhibition of recombinant human neprilysin(NEP).More data for this Ligand-Target Pair
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288076(((E)-2-Mercaptomethyl-3-phenyl-acryloylamino)-acet...)
Affinity DataKi:  4.90nMAssay Description:Compound was evaluated for inhibition of recombinant human neprilysin(NEP).More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288074((2-Benzyl-2-mercaptomethyl-3-phenyl-propionylamino...)
Affinity DataKi: >100nMAssay Description:Compound was evaluated for inhibition of recombinant human neprilysin(NEP).More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288077(CHEMBL81710 | [(2-Mercaptomethyl-indane-2-carbonyl...)
Affinity DataKi:  162nMAssay Description:Compound was evaluated for inhibition of recombinant human neprilysin(NEP).More data for this Ligand-Target Pair
In DepthDetails Article
TargetAngiotensin-converting enzyme(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50288076(((E)-2-Mercaptomethyl-3-phenyl-acryloylamino)-acet...)
Affinity DataKi:  380nMAssay Description:Compound was measured for the inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288075(((Z)-2-Mercaptomethyl-3-phenyl-acryloylamino)-acet...)
Affinity DataKi:  408nMAssay Description:Compound was evaluated for inhibition of recombinant human neprilysin(NEP).More data for this Ligand-Target Pair
In DepthDetails Article